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Crystallographic fragment screening and enhanced structural biology platform.
CrystalsFirst’s proprietary technology platform generates rapid high-quality insights into drug-target-interactions. The co-structure determination process - from protein crystal to 3D model - is accelerated by the factor of 5 to 10.
Applications are crystallographic fragment screen for FBDD and structural validation of hits from orthogonal screening techniques. Deliverables of crystallographic fragment screen are high hit rates, access to new chemical space for IP, and new modes of actions for early drug discovery.