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Home CSCS00020675338

Structure Info

Chemspace ID
CSCS00020675338 (Synthesis)
MFCD
MFCD12913912
IUPAC Name
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine dihydrochloride
Mol formula
C22H26Cl3FN4O3
Mol weight
520 Da
Catalog Number(s)
184475-56-7, 61586, AA00APBX, ADB5500082001, AG00APEP, APB184475567, AR00AQ3P, CSC020675338, D783710, FG103470, HY-50895B, JH185512, T63630

Properties

LogP
3.75
Heavy atoms count
33
Rotatable bond count
8
Number of rings
4
Carbon bond saturation, Fsp3
0.363
Polar surface area (Å)
69
Hydrogen bond acceptors count
7
Hydrogen bond donors count
1

SDS

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C22H26Cl3FN4O3
Zoom the structure
CSCS00020675338
 

Items Overall 11 items from 7 suppliers

SupplierLead timeShips fromPurityPackPrice, $Qty
Angene US10 daysUnited States
To:
9810 mg23
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Angene US10 daysUnited States
To:
9850 mg62
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Angene US10 daysUnited States
To:
98250 mg249
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Description: 4-(3-Chloro-4-fluorophenylamino)-7-methoxy-6-[3-(4-morpholinyl)propoxy]quinazoline dihydrochloride; CAS: 184475-56-7
Titan Scientific25 daysChina
To:
95100 mg1,482
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Description: Purity: 95%, RG(Reagent Grade); CAS: 474944-16-6
Targetmol Chemicals Inc30 daysUnited States
To:
9025 mg1,520
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Targetmol Chemicals Inc30 daysUnited States
To:
9050 mg1,980
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Targetmol Chemicals Inc30 daysUnited States
To:
90100 mg2,500
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Description: Gefitinib dihydrochloride is a potent, selective, orally active EGFR tyrosine kinase inhibitor (IC50: 33 nM). Gefitinib dihydrochloride selectively inhibits EGF-stimulated tumor cell growth with an IC50 value of 54 nM and blocks EGFR autophosphorylation in EGF-stimulated tumor cells. Gefitinib dihydrochloride induces autophagy and apoptosis, and can be used in studies of cancer-related diseases such as lung and breast cancer.; CAS: 184475-56-7
Alfa Chemistry Analytical ProductsTBDUnited States
To:
951 gPOA
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BOC SciencesTBDUnited States
To:
951 gPOA
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Description: CAS: 184475-56-7
MedChemExpressTBDUnited States
To:
901 mgPOA
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Description: Names: Gefitinib (dihydrochloride); ZD 1839 (dihydrochloride); Product Description: Gefitinib (ZD 1839) dihydrochloride is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC 50 of 33 nM. Gefitinib dihydrochloride selectively inhibits EGF-stimulated tumor cell growth (IC 50 of 54 nM) and blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib dihydrochloride also induces autophagy and cell apoptosis , which can be used for cancer related research, such as Lung cancer and breast cancer .; Target: Apoptosis;Autophagy;EGFR; CAS: 184475-56-7
MedChemExpress EUTBDSweden
To:
901 mgPOA
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Description: Names: Gefitinib (dihydrochloride); ZD 1839 (dihydrochloride); Product Description: Gefitinib (ZD 1839) dihydrochloride is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib dihydrochloride selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib dihydrochloride also induces autophagy and cell apoptosis, which can be used for cancer related research, such as Lung cancer and breast cancer ; Target: Apoptosis;Autophagy;EGFR; CAS: 184475-56-7
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