News and Events

Lead optimization transforms an initial active molecule into a true drug candidate by fine-tuning its structure, balancing activity, safety, and stability to unlock real therapeutic potential.

We are excited to share that our latest publication on Freedom Space 3.0 is now out!

This fall, Chemspace brings you an exclusive offer: 3D shape-based similarity screening of 1.76M compounds from Enamine Screening Collection - only 5,000 USD. 

Discovering new medicines has always been a challenge with an asterisk. The journey from an early idea in the lab to a finished drug on the market with traditional research methods usually takes years of hard work and enormous human and financial effort.

Join Olena Mishchuk, PhD, and Inna Volkova at BioJapan - the premier bio-industry partnering event - taking place in Yokohama, Japan, on October 8–10.

Chemspace is the largest online catalog of small molecules and biologics! With every update, we make this universe of chemistry even bigger and easier to navigate.

Cucurbiturils have become a subject of considerable interest within supramolecular chemistry, attributable to their distinctive host-guest characteristics and broad applicability across domains such as drug delivery, catalysis, molecular recognition, and materials science.

Check out our exclusive limited offer: AL-accelerated docking of a custom set (up to 100M compounds from Enamine REAL) for just 35,000 USD!

Discovering a new drug is like hunting for a needle in a haystack - except the haystack keeps growing while the search continues.

Chemspace is excited to join the Best of Show Awards at Discovery on Target 2025 with our V-SYNTHES approach!

We are excited to share that Uliana Matviienko, Inna Volkova, Mariia Tokova, and Kateryna Horbatok will be there representing Chemspace at booth #314.

We are thrilled to share that Olga Tarkhanova, PhD, and Rita Gaidar will be representing Chemspace at the RSC-BMCS / SCI 23rd Medicinal Chemistry Symposium in Cambridge, September 14–17!

Our AI-driven approach combines docking with Active Learning (AL), which addresses these challenges by intelligently guiding the search for promising compounds, performing only a fraction of the calculations.

VAV1 has re-emerged as a focus of interest for pharmaceutical companies due to its high potential role in the pathogenesis of autoimmune diseases.

Last Chance: Custom Compound Library for Just $10K!
This is your final opportunity to get a custom-designed compound library tailored to your target - for only $10K.

Every year, July 28 marks World Hepatitis Day – a global call to raise awareness, promote prevention, improve diagnosis, and expand access to treatment for all forms of viral hepatitis.

Lactate dehydrogenase A (LDHA) is a promising target in drug discovery due to its central role in glycolysis. Chemspace offers a carefully selected set of Biologics for studying LDHA.

On July 22, we celebrate World Brain Day, honoring the founding of the World Federation of Neurology and uniting the global community to promote brain health.

Following the screening of 3.9M compounds, we curated a library of 528 potent and novel type II kinase inhibitors.

Chemspace, LLC, Enamine, Ltd., and Orogen Therapeutics are excited to announce a strategic collaboration to enable next-generation REAL-driven DNA-encoded small molecule libraries (DELs). This partnership brings together the complementary strengths of the three companies to accelerate the search for innovative medicines.

We are excited to announce that Freedom Space 4.0 is now accessible for screening using Alipheron’s latest powerful tool, Pharos-3D.

Handling ultra-large chemical spaces like Enamine REAL Space (70B) or Chemspace Freedom Space 4.0 (142B) using traditional enumeration and scoring methods can take weeks and massive computing power.

Over the past few years, commercially available combinatorial libraries have expanded from billions to trillions of compounds, posing a fundamental computational and methodological challenge: how to explore such massive spaces efficiently and meaningfully? 

Great News! Chemspace databases are now searchable on the CHEESE Platform!

We are thrilled to announce our partnership with QDX, pioneers in revolutionizing molecular research through advanced computational technologies.