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Home Chemical search Search Results CSCS02495326161

Structure Info


Chemspace ID
CSCS02495326161 (Synthesis)
IUPAC Name
4-[(3S,3'S,3'aS,5'R,6'aS)-6-chloro-3'-(3-chloro-2-fluorophenyl)-1'-(cyclopropylmethyl)-2-oxo-1,2,3',3'a,4',5',6',6'a-octahydro-1'H-spiro[indole-3,2'-pyrrolo[3,2-b]pyrrol]-5'-yl]benzoic acid
Mol formula
C30H26Cl2FN3O3
Mol weight
566 Da
Catalog Number(s)
HY-100765, T14554

Properties

LogP
3.39
Heavy atoms count
39
Rotatable bond count
5
Number of rings
7
Carbon bond saturation, Fsp3
0.333
Polar surface area (Å)
82
Hydrogen bond acceptors count
5
Hydrogen bond donors count
3

SDS

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Items Overall 5 items from 3 suppliers

SupplierLead timeShips fromPurityPackPrice, $Qty
Targetmol Chemicals Inc30 daysUnited States
To:
9025 mg1,820
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Targetmol Chemicals Inc30 daysUnited States
To:
9050 mg2,380
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Targetmol Chemicals Inc30 daysUnited States
To:
90100 mg3,100
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Description: BI-0252 is an inhibitor of MDM2-p53 (IC50:4 nM). BI-0252 can induce tumor regressions in all animals of a mouse SJSA-1 xenograft. And it concomitant induction of the tumor protein p53 (TP53) target genes and markers of apoptosis.; CAS: 1818291-27-8
MedChemExpressTBDUnited States
To:
901 mgPOA
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Description: Names: BI-0252; Product Description: BI-0252 is an orally active, selective MDM2-p53 inhibitor with an IC50 of 4 nM. BI-0252 can induce tumor regressions in all animals of a mouse SJSA-1 xenograft, with concomitant induction of the tumor protein p53 (TP53) target genes and markers of apoptosis; Target: E1/E2/E3 Enzyme;MDM-2/p53; CAS: 1818291-27-8
MedChemExpress EUTBDSweden
To:
901 mgPOA
Go to cartEnquire
Description: Names: BI-0252; Product Description: BI-0252 is an orally active, selective MDM2-p53 inhibitor with an IC50 of 4 nM. BI-0252 can induce tumor regressions in all animals of a mouse SJSA-1 xenograft, with concomitant induction of the tumor protein p53 (TP53) target genes and markers of apoptosis; Target: E1/E2/E3 Enzyme;MDM-2/p53; CAS: 1818291-27-8
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