Structure Info
- Chemspace ID
- CSCS02495326161 (Synthesis)
- IUPAC Name
- 4-[(3S,3'S,3'aS,5'R,6'aS)-6-chloro-3'-(3-chloro-2-fluorophenyl)-1'-(cyclopropylmethyl)-2-oxo-1,2,3',3'a,4',5',6',6'a-octahydro-1'H-spiro[indole-3,2'-pyrrolo[3,2-b]pyrrol]-5'-yl]benzoic acid
- Mol formula
- C30H26Cl2FN3O3
- Mol weight
- 566 Da
- Catalog Number(s)
- HY-100765, T14554
- Copy structure to query editor
- SMILES
- INCHI
- INCHI key
- MOL
Properties
- LogP
- 3.39
- Heavy atoms count
- 39
- Rotatable bond count
- 5
- Number of rings
- 7
- Carbon bond saturation, Fsp3
- 0.333
- Polar surface area (Å)
- 82
- Hydrogen bond acceptors count
- 5
- Hydrogen bond donors count
- 3
- Zoom the structure
- CSCS02495326161
Items Overall 5 items from 3 suppliers
Supplier | Lead time | Ships from | Purity | Pack | Price, $ | Qty |
---|---|---|---|---|---|---|
Targetmol Chemicals Inc | 30 days | United States To: | 90 | 25 mg | 1,820 | |
Targetmol Chemicals Inc | 30 days | United States To: | 90 | 50 mg | 2,380 | |
Targetmol Chemicals Inc | 30 days | United States To: | 90 | 100 mg | 3,100 | |
Description: BI-0252 is an inhibitor of MDM2-p53 (IC50:4 nM). BI-0252 can induce tumor regressions in all animals of a mouse SJSA-1 xenograft. And it concomitant induction of the tumor protein p53 (TP53) target genes and markers of apoptosis.; CAS: 1818291-27-8 | ||||||
MedChemExpress | TBD | United States To: | 90 | 1 mg | POA | |
Description: Names: BI-0252; Product Description: BI-0252 is an orally active, selective MDM2-p53 inhibitor with an IC50 of 4 nM. BI-0252 can induce tumor regressions in all animals of a mouse SJSA-1 xenograft, with concomitant induction of the tumor protein p53 (TP53) target genes and markers of apoptosis; Target: E1/E2/E3 Enzyme;MDM-2/p53; CAS: 1818291-27-8 | ||||||
MedChemExpress EU | TBD | Sweden To: | 90 | 1 mg | POA | |
Description: Names: BI-0252; Product Description: BI-0252 is an orally active, selective MDM2-p53 inhibitor with an IC50 of 4 nM. BI-0252 can induce tumor regressions in all animals of a mouse SJSA-1 xenograft, with concomitant induction of the tumor protein p53 (TP53) target genes and markers of apoptosis; Target: E1/E2/E3 Enzyme;MDM-2/p53; CAS: 1818291-27-8 |
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