Structure Info
- Chemspace ID
- CSCS06744480053 (Synthesis)
- MFCD
- MFCD09873271
- IUPAC Name
- 7-{[3-({4-[(3-chloro-4-fluorophenyl)amino]-6-methoxyquinazolin-7-yl}oxy)propyl]amino}-N,N-dimethyl-2,1,3-benzoxadiazole-4-sulfonamide
- Mol formula
- C26H25ClFN7O5S
- Mol weight
- 602 Da
- Catalog Number(s)
- AG02DHZU, BN88882, HY-152098, T75015
- Copy structure to query editor
- SMILES
- INCHI
- INCHI key
- MOL
Properties
- LogP
- 3.63
- Heavy atoms count
- 41
- Rotatable bond count
- 10
- Number of rings
- 5
- Carbon bond saturation, Fsp3
- 0.23
- Polar surface area (Å)
- 145
- Hydrogen bond acceptors count
- 10
- Hydrogen bond donors count
- 2
- Zoom the structure
- CSCS06744480053
Items Overall 5 items from 2 suppliers
| Supplier | Lead time | Ships from | Purity | Pack | Price, $ | Qty |
|---|---|---|---|---|---|---|
| Angene International Limited | 15 days | China To: | 99 | 5 mg | 726 | |
| Angene International Limited | 15 days | China To: | 99 | 10 mg | 1,106 | |
| Angene International Limited | 15 days | China To: | 99 | 25 mg | 2,118 | |
| Angene International Limited | 15 days | China To: | 99 | 50 mg | 3,299 | |
Description: HX103; CAS: 2566466-98-4 | ||||||
| Targetmol Chemicals Inc | TBD | United States To: | 90 | 1 mg | POA | |
Description: HX103, an epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI)-based fluorogenic probe, exhibits selective inhibition towards various EGFR mutations, including EGFR 19 del, EGFR L858R, EGFR wild type, and EGFR T790M, with respective IC50 values of 1.3, 1.5, 4.0, and 977 nM. It is utilized for quantifying active-EGFR to foresee agent sensitivity in NSCLC (non-small cell lung cancer) patients harboring EGFR-activating mutations [1].; CAS: 2566466-98-4 | ||||||
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