Structure Info
- Chemspace ID
- CSCS06744597672 (Synthesis)
- IUPAC Name
- methyl (2S,3R,4R,5S,6R)-10-cyano-2,3-dihydroxy-12-methoxy-6-(4-methoxyphenyl)-5-phenyl-7-oxatricyclo[6.4.0.0²,⁶]dodeca-1(8),9,11-triene-4-carboxylate
- Mol formula
- C28H25NO7
- Mol weight
- 488 Da
- Catalog Number(s)
- HY-148451, T72943
- Copy structure to query editor
- SMILES
- INCHI
- INCHI key
- MOL
Properties
- LogP
- 2.91
- Heavy atoms count
- 36
- Rotatable bond count
- 6
- Number of rings
- 5
- Carbon bond saturation, Fsp3
- 0.285
- Polar surface area (Å)
- 118
- Hydrogen bond acceptors count
- 7
- Hydrogen bond donors count
- 2
- Zoom the structure
- CSCS06744597672
Items Overall 5 items from 3 suppliers
Supplier | Lead time | Ships from | Purity | Pack | Price, $ | Qty |
---|---|---|---|---|---|---|
Targetmol Chemicals Inc | 30 days | United States To: | 90 | 25 mg | 1,820 | |
Targetmol Chemicals Inc | 30 days | United States To: | 90 | 50 mg | 2,380 | |
Targetmol Chemicals Inc | 30 days | United States To: | 90 | 100 mg | 3,100 | |
Description: eIF4A3-IN-17, a silvestrol analogue, disrupts the assembly of the eIF4F translation complex, exhibiting EC50 values of 0.9, 15, and 1.8 nM for myc-LUC, tub-LUC, and growth inhibition of MBA-MB-231 cells, respectively. This compound holds potential for research in human cancer pathogenesis [1].; CAS: 1402931-75-2 | ||||||
MedChemExpress | TBD | United States To: | 90 | 1 mg | POA | |
Description: Names: eIF4A3-IN-17; Product Description: eIF4A3-IN-17 (compound 61) is a silvestrol (HY-13251) analogue. eIF4A3-IN-17 interferes the assembling of eIF4F translation complex with EC 50 s of 0.9, 15 and 1.8 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-17 can be used for the research of human cancer pathogenesis .; Target: Eukaryotic Initiation Factor (eIF); CAS: 1402931-75-2 | ||||||
MedChemExpress EU | TBD | Sweden To: | 90 | 1 mg | POA | |
Description: Names: eIF4A3-IN-17; Product Description: eIF4A3-IN-17 (compound 61) is a silvestrol (HY-13251) analogue. eIF4A3-IN-17 interferes the assembling of eIF4F translation complex with EC50s of 0.9, 15 and 1.8 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-17 can be used for the research of human cancer pathogenesis; Target: Eukaryotic Initiation Factor (eIF); CAS: 1402931-75-2 |
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