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Home Chemical search Search Results CSCS20465146760

Structure Info

Chemspace ID
CSCS20465146760 (Synthesis)
IUPAC Name
methyl (1S,14E,16R,19S)-14-ethylidene-6-hydroxy-2-methyl-18-oxa-2,12-diazahexacyclo[13.3.2.0¹,⁹.0³,⁸.0⁹,¹⁶.0¹²,¹⁹]icosa-3,5,7-triene-16-carboxylate
Mol formula
C22H26N2O4
Mol weight
382 Da
Catalog Number(s)
HY-122189

Properties

LogP
2.55
Heavy atoms count
28
Rotatable bond count
2
Number of rings
6
Carbon bond saturation, Fsp3
0.59
Polar surface area (Å)
62
Hydrogen bond acceptors count
5
Hydrogen bond donors count
1

SDS

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C22H26N2O4
Zoom the structure
CSCS20465146760
 

Items Overall 4 items from 2 suppliers

SupplierLead timeShips fromPurityPackPrice, $Qty
MedChemExpress30 daysUnited States
To:
901 mg255
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MedChemExpress30 daysUnited States
To:
905 mg1,019
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Description: Names: Akuammine; (-)-Akuammine; Vincamajoridine; Product Description: Akuammine is an indole alkaloid that has been found in Picralima nitida and has analgesic activity. It selectively binds to the μ- and κ-opioid receptors over the δ-opioid receptor (Kis=0.3, 1.68, and 10.4 μM for the human receptors, respectively). Akuammine inhibits forskolin-induced cAMP production in HEK293 cells expressing human μ- or κ-opioid receptors ( IC 50 s=2.6 and 0.073 μM, respectively). It increases the latency to withdrawal in the tail-flick or hot plate test in mice when administered at a dose of 60 mg/kg.; CAS: 3512-87-6
MedChemExpress EU30 daysSweden
To:
901 mg268
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MedChemExpress EU30 daysSweden
To:
905 mg1,074
Go to cartEnquire
Description: Names: Akuammine; (-)-Akuammine; Vincamajoridine; Product Description: Akuammine is an indole alkaloid that has been found in Picralima nitida and has analgesic activity. It selectively binds to the μ- and κ-opioid receptors over the δ-opioid receptor (Kis=0.3, 1.68, and 10.4 μM for the human receptors, respectively). Akuammine inhibits forskolin-induced cAMP production in HEK293 cells expressing human μ- or κ-opioid receptors (IC50s=2.6 and 0.073 μM, respectively). It increases the latency to withdrawal in the tail-flick or hot plate test in mice when administered at a dose of 60 mg/kg.; CAS: 3512-87-6
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