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Home CSCS20620705525

Structure Info

Chemspace ID
CSCS20620705525 (Synthesis)
IUPAC Name
4-methylbenzene-1-sulfonic acid; 7-{[(3aR,5R,6aS)-2-methyl-octahydrocyclopenta[c]pyrrol-5-yl]methoxy}-N-(3,4-dichloro-2-fluorophenyl)-6-methoxyquinazolin-4-amine
Mol formula
C31H33Cl2FN4O5S
Mol weight
664 Da
Catalog Number(s)
HY-13314A, T201865

Properties

LogP
5.25
Heavy atoms count
44
Rotatable bond count
7
Number of rings
6
Carbon bond saturation, Fsp3
0.354
Polar surface area (Å)
60
Hydrogen bond acceptors count
6
Hydrogen bond donors count
1

SDS

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C31H33Cl2FN4O5S
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CSCS20620705525
 

Items Overall 3 items from 3 suppliers

SupplierLead timeShips fromPurityPackPrice, $Qty
MedChemExpressTBDUnited States
To:
901 mgPOA
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Description: Names: Tesevatinib (tosylate); XL-647 (tosylate); EXEL-7647 (tosylate); KD-019(tosylate); Product Description: Tesevatinib (XL-647) tosylate is an orally available, blood-brain barrier-penetrant inhibitor of the epidermal growth factor receptor ( EGFR ). Tesevatinib tosylate significantly reduces cellular viability, with IC 50 values of 11 nM and 102 nM in GBM12 and GBM6, respectively. Tesevatinib tosylate also inhibits HER2 ( IC 50 =16.1 nM), VEGFR2 ( IC 50 =1.5 nM), and Src ( IC 50 =10.3 nM). Tesevatinib tosylate can inhibit tumor proliferation and exhibits antitumor activity .; Target: EGFR;Src;VEGFR; CAS: 1000599-06-3
MedChemExpress EUTBDSweden
To:
901 mgPOA
Go to cartEnquire
Description: Names: Tesevatinib (tosylate); XL-647 (tosylate); EXEL-7647 (tosylate); KD-019(tosylate); Product Description: Tesevatinib (XL-647) tosylate is an orally available, blood-brain barrier-penetrant inhibitor of the epidermal growth factor receptor (EGFR). Tesevatinib tosylate significantly reduces cellular viability, with IC50 values of 11 nM and 102 nM in GBM12 and GBM6, respectively. Tesevatinib tosylate also inhibits HER2 (IC50=16.1 nM), VEGFR2 (IC50=1.5 nM), and Src (IC50=10.3 nM). Tesevatinib tosylate can inhibit tumor proliferation and exhibits antitumor activity; Target: EGFR;Src;VEGFR; CAS: 1000599-06-3
Targetmol Chemicals IncTBDUnited States
To:
901 mgPOA
Go to cartEnquire
Description: Tesevatinib tosylate (XL-647 tosylate) is an orally administered epidermal growth factor receptor (EGFR) inhibitor that can cross the blood-brain barrier. It significantly reduces cell viability with IC50 values of 11 nM and 102 nM in GBM12 and GBM6, respectively. Additionally, Tesevatinib tosylate inhibits HER2 (IC50=16.1 nM), VEGFR2 (IC50=1.5 nM), and Src (IC50=10.3 nM), demonstrating antitumor activity by inhibiting tumor proliferation.; CAS: 1000599-06-3
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