Structure Info
- Chemspace ID
- CSCS20620705757 (Synthesis)
- IUPAC Name
- N-(3-chloro-2-fluorophenyl)-6-[4-({[2,6-dimethoxy-4-({2-methyl-[1,1'-biphenyl]-3-yl}methoxy)phenyl]methyl}amino)butoxy]-7-methoxyquinazolin-4-amine
- Mol formula
- C42H42ClFN4O5
- Mol weight
- 737 Da
- Catalog Number(s)
- HY-159101
- Copy structure to query editor
- SMILES
- INCHI
- INCHI key
- MOL
Properties
- LogP
- 9.24
- Heavy atoms count
- 53
- Rotatable bond count
- 17
- Number of rings
- 6
- Carbon bond saturation, Fsp3
- 0.238
- Polar surface area (Å)
- 96
- Hydrogen bond acceptors count
- 9
- Hydrogen bond donors count
- 2
- Zoom the structure
- CSCS20620705757
Items Overall 2 items from 2 suppliers
| Supplier | Lead time | Ships from | Purity | Pack | Price, € | Qty |
|---|---|---|---|---|---|---|
| MedChemExpress | TBD | United States To: | 90 | 1 mg | POA | |
Description: Names: EP26; Product Description: EP26 is a potent and orally active EGFR and PD-L1 inhibitor with IC 50 values of 48.6 nM, 1.77 µM, respectively. EP26 decreased the protein expression of p-EGFR. EP26 induces cell cycle arrest at G0/G1 phase. EP26 has the potential for the research of glioblastoma .; Target: EGFR;PD-1/PD-L1 | ||||||
| MedChemExpress EU | TBD | Sweden To: | 90 | 1 mg | POA | |
Description: Names: EP26; Product Description: EP26 is a potent and orally active EGFR and PD-L1 inhibitor with IC50 values of 48.6 nM, 1.77 µM, respectively. EP26 decreased the protein expression of p-EGFR. EP26 induces cell cycle arrest at G0/G1 phase. EP26 has the potential for the research of glioblastoma; Target: EGFR;PD-1/PD-L1 | ||||||
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