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Home CSSS00000051173

Structure Info


Chemspace ID
CSSS00000051173 (In-Stock Screening Compounds)
CAS
184475-35-2
MFCD
MFCD04307832
IUPAC Name
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine
Mol formula
C22H24ClFN4O3
Mol weight
447 Da
Catalog Number(s)
10496, 13166, 21432, 101029, 306578, 34a_100015190902_100000748698, 37923, A109874, A8219, AA0039I6, AB52186, ACM184475352, ACM184475352-2, ACS-524, ADB92939001, AG0039KY, AJ52186, AOS0039KY, APB184475352, AR003A9Y, ArZ-UP080933, ArZ-UP480321, B0084-306578, BB4LS-EN300-123024, BBF-04570, BD131918, BG164498, BISN0101, CB14314, CD31002885, CFN90011, CSC000051173, CT1946, DZB66449, EN300-123024, F079438, F231003, FG10816, G0546, G304000, H018, HY-50895, J10250, J94474, KS-1204, LAN-B42345, LN00175798, LQT-B42422, M12848, OSSL_882918, R633575, S1025, SAB-025327, SC-18023, SM00066, STK621310, SY002154, SYN1042, T1181, YBD160510, Z1546610485, Z1551429741, ZX-AE020634, ZX-CY002097, scs-524

Properties

LogP
3.75
Heavy atoms count
31
Rotatable bond count
8
Number of rings
4
Carbon bond saturation, Fsp3
0.363
Polar surface area (Å)
69
Hydrogen bond acceptors count
7
Hydrogen bond donors count
1

SDS

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Items Overall 36 items from 8 suppliers

SupplierLead timeShips fromPurityPackPrice, $Qty
Enamine Ltd5 daysUkraine
To:
901 mg83
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Enamine Ltd5 daysUkraine
To:
902 mg85
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Enamine Ltd5 daysUkraine
To:
905 mg91
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Enamine Ltd5 daysUkraine
To:
9010 mg102
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Enamine Ltd5 daysUkraine
To:
9020 mg123
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MedChemExpress10 daysUnited States
To:
99100 mg60
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MedChemExpress10 daysUnited States
To:
99500 mg72
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MedChemExpress10 daysUnited States
To:
991 g90
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MedChemExpress10 daysUnited States
To:
995 g180
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MedChemExpress10 daysUnited States
To:
9910mM/1mL66
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Description: Names: Gefitinib; ZD1839; Product Description: Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC 50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC 50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy and cell apoptosis , which can be used for cancer related research, such as Lung cancer and breast cancer .; Target: Apoptosis;Autophagy;EGFR; CAS: 184475-35-2
Apexbio Technology LLC10 daysUnited States
To:
99100 mg67
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Apexbio Technology LLC10 daysUnited States
To:
99250 mg77
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Apexbio Technology LLC10 daysUnited States
To:
9910mM (in 1mL DMSO)61
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Description: Name: Gefitinib (ZD1839); Selective EGFR inhibitor; Format: a solid; CAS: 184475-35-2
Key Organics Limited (BIONET)10 daysUnited Kingdom
To:
971 mg61
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Key Organics Limited (BIONET)10 daysUnited Kingdom
To:
975 mg92
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Key Organics Limited (BIONET)10 daysUnited Kingdom
To:
9710 mg128
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MedChemExpress EU10 daysSweden
To:
99100 mg63
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MedChemExpress EU10 daysSweden
To:
99500 mg75
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MedChemExpress EU10 daysSweden
To:
991 g95
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MedChemExpress EU10 daysSweden
To:
995 g190
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MedChemExpress EU10 daysSweden
To:
9910mM/1mL69
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Description: Names: Gefitinib; ZD1839; Product Description: Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy and cell apoptosis, which can be used for cancer related research, such as Lung cancer and breast cancer ; Target: Apoptosis;Autophagy;EGFR; CAS: 184475-35-2
Princeton Biomolecular Research10 daysUnited States
To:
901 mg88
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Princeton Biomolecular Research10 daysUnited States
To:
902 mg94
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Princeton Biomolecular Research10 daysUnited States
To:
905 mg99
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Princeton Biomolecular Research10 daysUnited States
To:
9010 mg116
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Princeton Biomolecular Research10 daysUnited States
To:
9015 mg132
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Princeton Biomolecular Research10 daysUnited States
To:
9020 mg143
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Princeton Biomolecular Research10 daysUnited States
To:
9050 mg231
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Princeton Biomolecular Research10 daysUnited States
To:
90100 mg297
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Princeton Biomolecular Research10 daysUnited States
To:
903 umol94
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Princeton Biomolecular Research10 daysUnited States
To:
905 umol99
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ChemFaces12 daysChina
To:
901 mg6
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Description: CAS: 184475-35-2
Targetmol Chemicals Inc30 daysUnited States
To:
99100 mg50
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Targetmol Chemicals Inc30 daysUnited States
To:
99500 mg57
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Targetmol Chemicals Inc30 daysUnited States
To:
991 g74
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Targetmol Chemicals Inc30 daysUnited States
To:
995 g148
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Description: Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations. Gefitinib has antitumor activity and is used for the treatment of EGFR-mutated non-small-cell lung cancers. Gefitinib administration RESULTS in the development of the EGFR C797S resistance mutation.; CAS: 184475-35-2
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