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Home CSSS00000054742

Structure Info


Chemspace ID
CSSS00000054742 (In-Stock Screening Compounds)
CAS
322-79-2
MFCD
MFCD00866793
IUPAC Name
2-(acetyloxy)-4-(trifluoromethyl)benzoic acid
Mol formula
C10H7F3O4
Mol weight
248 Da
Catalog Number(s)
30274, 38332, 66043, 151838, 322-79-2, A626746, AA007GWY, AC034399, ACDS-034180, ACM322792, AD48414, ADB48460001, AG-19716, AG007GZQ, AL48414, AOS007GZQ, AP322792, APS322792, AR007HOQ, AS-63983, B1461, BB4LS-BD42634, BBV-356733709, BD42634, CSC000054742, D480545, EN300-18567716, F828198, FT28493, HY-B0531, I589, J55536, JH671521, LAN-B14840, LN00189377, LP050376, LQT-B14874, M14050, R007893, S3200, SAB-029683, SC-16156, T0705, T3601, T72290, T72290-0.25G, T793600, W-106849

Properties

LogP
2.12
Heavy atoms count
17
Rotatable bond count
4
Number of rings
1
Carbon bond saturation, Fsp3
0.2
Polar surface area (Å)
64
Hydrogen bond acceptors count
3
Hydrogen bond donors count
1

SDS

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Items Overall 16 items from 3 suppliers

SupplierLead timeShips fromPurityPackPrice, $Qty
MedChemExpress10 daysUnited States
To:
995 mg50
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MedChemExpress10 daysUnited States
To:
9910 mg80
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MedChemExpress10 daysUnited States
To:
9950 mg250
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MedChemExpress10 daysUnited States
To:
99100 mg400
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MedChemExpress10 daysUnited States
To:
9910mM/1mL55
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Description: Names: Triflusal; Product Description: Triflusal irreversibly inhibits the production of thromboxane-B2 in platelets by acetylating cycloxygenase-1.Target: COXTriflusal at 10 mM, 100 mM and 1 M decreases LDH efflux in rat brain slices after anoxia/reoxygenation by 24%, 35% and 49% respectively. Triflusal also reduces inducible NO synthase activity by 18%, 21% and 30% Triflusal (10 mg/kg i.v.) reduces platelet deposition on subendothelium-induced primary thrombus by about 68% in rabbits. Triflusal (10 mg/kg i.v.) reduces platelet deposition on a fresh thrombus formed over tunica media by about 48% in rabbits. Triflusal (40 mg/kg p.o.) reduces platelet deposition on a primary thrombus triggered by subendothelium and tunica media by 53% in rabbits. Triflusal (40 mg/kg p.o.) significantly reduces Cox-2 mRNA levels and protein levels without influence Cox-1 mRNA levels on the vascular wall in rabbits Triflusal (600 mg/day for 5 days) results in an increase in NO production by neutrophils and an increase in endothelial nitric oxide synthase (eNOS) protein expression in neutrophils in healthy volunteers ; Target: COX; CAS: 322-79-2
MedChemExpress EU10 daysSweden
To:
995 mg53
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MedChemExpress EU10 daysSweden
To:
9910 mg68
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MedChemExpress EU10 daysSweden
To:
9925 mg100
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MedChemExpress EU10 daysSweden
To:
9950 mg132
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MedChemExpress EU10 daysSweden
To:
99100 mg173
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MedChemExpress EU10 daysSweden
To:
99500 mg316
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MedChemExpress EU10 daysSweden
To:
9910mM/1mL58
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Description: Names: Triflusal; Product Description: Triflusal irreversibly inhibits the production of thromboxane-B2 in platelets by acetylating cycloxygenase-1.Target: COXTriflusal at 10 mM, 100 mM and 1 M decreases LDH efflux in rat brain slices after anoxia/reoxygenation by 24%, 35% and 49% respectively. Triflusal also reduces inducible NO synthase activity by 18%, 21% and 30% Triflusal (10 mg/kg i.v.) reduces platelet deposition on subendothelium-induced primary thrombus by about 68% in rabbits. Triflusal (10 mg/kg i.v.) reduces platelet deposition on a fresh thrombus formed over tunica media by about 48% in rabbits. Triflusal (40 mg/kg p.o.) reduces platelet deposition on a primary thrombus triggered by subendothelium and tunica media by 53% in rabbits. Triflusal (40 mg/kg p.o.) significantly reduces Cox-2 mRNA levels and protein levels without influence Cox-1 mRNA levels on the vascular wall in rabbits Triflusal (600 mg/day for 5 days) results in an increase in NO production by neutrophils and an increase in endothelial nitric oxide synthase (eNOS) protein expression in neutrophils in healthy volunteers ; Target: COX; CAS: 322-79-2
Apexbio Technology LLC10 daysUnited States
To:
995 mg55
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Apexbio Technology LLC10 daysUnited States
To:
9910 mg88
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Apexbio Technology LLC10 daysUnited States
To:
9925 mg209
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Apexbio Technology LLC10 daysUnited States
To:
9910mM (in 1mL DMSO)55
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Description: Name: Triflusal; COX inhibitor; Format: a solid; CAS: 322-79-2
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