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Home Chemical search Search Results CSSS00000736165

Structure Info

Chemspace ID
CSSS00000736165 (In-Stock Screening Compounds)
CAS
134029-62-2
MFCD
MFCD03427315
IUPAC Name
1,2,3-trimethoxy-5-[(1E)-2-(4-methoxyphenyl)ethenyl]benzene
Mol formula
C18H20O4
Mol weight
300 Da
Catalog Number(s)
134029-49-5, A577431, AA009JOU, ACM134029495, AE45322, AG009JRM, AR009KGM, BD161471, CSC000736165, EN300-21686167, FT66531, G13205, HY-137977, LN04604631, M28078, MS-24329, Q65678, T298908, T36674, U74814, Y3141586, ZXC243381

Properties

LogP
3.68
Heavy atoms count
22
Rotatable bond count
6
Number of rings
2
Carbon bond saturation, Fsp3
0.222
Polar surface area (Å)
37
Hydrogen bond acceptors count
4
Hydrogen bond donors count
0

SDS

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C18H20O4
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CSSS00000736165
 

Items Overall 17 items from 3 suppliers

SupplierLead timeShips fromPurityPackPrice, $Qty
MedChemExpress10 daysUnited States
To:
995 mg62
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MedChemExpress10 daysUnited States
To:
9910 mg100
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MedChemExpress10 daysUnited States
To:
9925 mg200
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MedChemExpress10 daysUnited States
To:
9950 mg350
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MedChemExpress10 daysUnited States
To:
9910mM/1mL68
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Description: Names: DMU-212; Product Description: DMU-212 is a methylated derivative of Resveratrol (HY-16561), with antimitotic, anti-proliferative, antioxidant and apoptosis promoting activities. DMU-212 induces mitotic arrest via induction of apoptosis and activation of ERK1/2 protein. DMU-212 has orally active .; Target: Apoptosis;ERK; CAS: 134029-62-2
MedChemExpress EU10 daysSweden
To:
995 mg65
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MedChemExpress EU10 daysSweden
To:
9910 mg105
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MedChemExpress EU10 daysSweden
To:
9925 mg211
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MedChemExpress EU10 daysSweden
To:
9950 mg369
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MedChemExpress EU10 daysSweden
To:
9910mM/1mL71
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Description: Names: DMU-212; Product Description: DMU-212 is a methylated derivative of Resveratrol (HY-16561), with antimitotic, anti-proliferative, antioxidant and apoptosis promoting activities. DMU-212 induces mitotic arrest via induction of apoptosis and activation of ERK1/2 protein. DMU-212 has orally active; Target: Apoptosis;ERK; CAS: 134029-62-2
Targetmol Chemicals Inc30 daysUnited States
To:
992 mg30
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Targetmol Chemicals Inc30 daysUnited States
To:
995 mg48
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Targetmol Chemicals Inc30 daysUnited States
To:
9910 mg80
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Targetmol Chemicals Inc30 daysUnited States
To:
9925 mg163
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Targetmol Chemicals Inc30 daysUnited States
To:
9950 mg288
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Targetmol Chemicals Inc30 daysUnited States
To:
99100 mg428
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Targetmol Chemicals Inc30 daysUnited States
To:
99500 mg969
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Description: DMU-212 is a methylated derivative of resveratrol with antimitotic, anti-proliferative, antioxidant, and apoptosis-promoting activities. It induces mitotic arrest, apoptosis, and activation of ERK1/2 protein and has oral activity[1][2]. DMU-212 (0.3125-40 μM) inhibits the growth of human melanoma cells (A375, MeWo, Bro, M5)[1]. At concentrations of 30-50 μM over 24 hours, it upregulates cell cycle inhibitors, induces apoptosis, and activates ERK in A375 cells[1]. DMU-212 also induces G2/M arrest and apoptosis in cancer cells[1]. In a xenograft model of human ovarian cancer with six-week-old SCID female mice (20-24 g), DMU-212 (50 mg/kg, administered orally three times a week for 14 days) inhibits tumor growth[2]. [1]. Vasilis Pericles Androutsopoulos, et al. Activation of ERK1/2 is required for the antimitotic activity of the resveratrol analogue 3,4,5,4'-tetramethoxystilbene (DMU-212) in human melanoma cells. Exp Dermatol. 2015 Aug;24(8):632-4. [2]. Hanna Piotrowska, et al. DMU-212 inhibits tumor growth in xenograft model of human ovarian cancer. Biomed Pharmacother. 2014 May;68(4):397-400.; CAS: 134029-62-2
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