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Home CSSS00015193841

Structure Info

Chemspace ID
CSSS00015193841 (In-Stock Screening Compounds)
CAS
1626387-80-1
MFCD
MFCD29058564
IUPAC Name
4-[(3-chloro-2-fluorophenyl)amino]-7-methoxyquinazolin-6-yl (2R)-2,4-dimethylpiperazine-1-carboxylate
Mol formula
C22H23ClFN5O3
Mol weight
460 Da
Catalog Number(s)
19931, 21504, 42354, 134385, 42354-0.1G, 470884, 9479AL, A171107, A808165, AA001T74, AA84396, ACS-1596, AG001T9W, AI84396, AOS001T9W, AR001TYW, AS-74755, AXPR01202, B0084-470884, B5962, BD434982, CD31003134, CSC015193841, D543569, FA137650, H997603, HY-18750, JH166119, LAN-B65809, LN02183823, M12405, M15301, S7971, SC-A2036, T3659, Y0974670, Y1041576, Z2471604138, ZXC133350, scs-1596

Properties

LogP
4.03
Heavy atoms count
32
Rotatable bond count
5
Number of rings
4
Carbon bond saturation, Fsp3
0.318
Polar surface area (Å)
80
Hydrogen bond acceptors count
6
Hydrogen bond donors count
1

SDS

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C22H23ClFN5O3
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CSSS00015193841
 

Items Overall 22 items from 5 suppliers

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MedChemExpress10 daysUnited States
To:
995 mg32
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MedChemExpress10 daysUnited States
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9910 mg50
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MedChemExpress10 daysUnited States
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9950 mg110
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MedChemExpress10 daysUnited States
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99100 mg170
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MedChemExpress10 daysUnited States
To:
9910mM/1mL55
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Description: Names: Zorifertinib; AZD3759; Product Description: Zorifertinib (AZD3759) is a potent, orally active, central nervous system-penetrant, EGFR inhibitor. At K m ATP concentrations, the IC 50 s are 0.3, 0.2, and 0.2 nM for EGFR wt , EGFR L858R , and EGFR exon 19Del , respectively. Zorifertinib induces cancer cell apoptosis . Zorifertinib has antitumor activity, and can be used for NSCLC, HCC etc. research .; Target: Apoptosis;EGFR; CAS: 1626387-80-1
MedChemExpress EU10 daysSweden
To:
995 mg34
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MedChemExpress EU10 daysSweden
To:
9910 mg53
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MedChemExpress EU10 daysSweden
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9950 mg116
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MedChemExpress EU10 daysSweden
To:
99100 mg180
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MedChemExpress EU10 daysSweden
To:
9910mM/1mL58
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Description: Names: Zorifertinib; AZD3759; Product Description: Zorifertinib (AZD3759) is a potent, orally active, central nervous system-penetrant, EGFR inhibitor. At Km ATP concentrations, the IC50s are 0.3, 0.2, and 0.2 nM for EGFRwt, EGFRL858R, and EGFRexon 19Del, respectively. Zorifertinib induces cancer cell apoptosis. Zorifertinib has antitumor activity, and can be used for NSCLC, HCC etc. research; Target: Apoptosis;EGFR; CAS: 1626387-80-1
Key Organics Limited (BIONET)10 daysUnited Kingdom
To:
971 mg53
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Key Organics Limited (BIONET)10 daysUnited Kingdom
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975 mg62
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Key Organics Limited (BIONET)10 daysUnited Kingdom
To:
9710 mg75
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Apexbio Technology LLC10 daysUnited States
To:
995 mg55
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Apexbio Technology LLC10 daysUnited States
To:
9910 mg77
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Apexbio Technology LLC10 daysUnited States
To:
9950 mg99
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Apexbio Technology LLC10 daysUnited States
To:
99100 mg154
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Apexbio Technology LLC10 daysUnited States
To:
9910mM (in 1mL DMSO)89
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Description: Name: AZD3759; EGFR inhibitor，oral active; Format: a solid; CAS: 1626387-80-1
Targetmol Chemicals Inc30 daysUnited States
To:
9925 mg37
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Targetmol Chemicals Inc30 daysUnited States
To:
9950 mg53
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Targetmol Chemicals Inc30 daysUnited States
To:
99100 mg83
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Targetmol Chemicals Inc30 daysUnited States
To:
99200 mg122
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Description: Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor. The IC50 values were 0.2, 0.3 and 0.2 nM for EGFR L858R mutant, TK wild-type, and Exon 19Del enzymes, respectively.; CAS: 1626387-80-1
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