Structure Info
- Chemspace ID
- CSSS00016991211 (In-Stock Screening Compounds)
- CAS
- 141-05-9
- MFCD
- MFCD00009191
- IUPAC Name
- 1,4-diethyl (2Z)-but-2-enedioate
- Mol formula
- C8H12O4
- Mol weight
- 172 Da
- Catalog Number(s)
- 141-05-9, 58455, A043, A200510, A490016045, AA001FN9, AA66833, ACM141059, ACM141059-2, ACM1410591, AG001FQ1, AI66833, AOS001FQ1, AP141059, AR001GF1, B6151, B697415, BB0294961, BB4LS-EN300-344747, BBV-108665411, BD124714, BS-15532, CD45000553, CM195302, CS-0017148, CSC016991211, D444535, D699054, D70233, EN300-344747, F1908-0131, F449208, FD38599, HY-Y1147, J95964, JH632682, LAN-B66846, LN00237957, LP018027, LP018030, M0010, M23567, OR1012871, PB3235043133, S4712, SAB-046949, T21480, Y1041231, Z3234965665, ZX-ARV15992, ZXC133017
- Copy structure to query editor
- SMILES
- INCHI
- INCHI key
- MOL
Properties
- LogP
- 1.43
- Heavy atoms count
- 12
- Rotatable bond count
- 6
- Number of rings
- 0
- Carbon bond saturation, Fsp3
- 0.5
- Polar surface area (Å)
- 53
- Hydrogen bond acceptors count
- 2
- Hydrogen bond donors count
- 0
- Zoom the structure
- CSSS00016991211
Items Overall 17 items from 6 suppliers
| Supplier | Lead time | Ships from | Purity | Pack | Price, $ | Qty |
|---|---|---|---|---|---|---|
| Enamine Ltd | 5 days | Ukraine To: | 90 | 1 mg | 104 | |
| Enamine Ltd | 5 days | Ukraine To: | 90 | 2 mg | 108 | |
| Enamine Ltd | 5 days | Ukraine To: | 90 | 5 mg | 118 | |
| Enamine Ltd | 5 days | Ukraine To: | 90 | 10 mg | 135 | |
| Enamine Ltd | 5 days | Ukraine To: | 90 | 20 mg | 169 | |
| Key Organics Limited (BIONET) | 10 days | United Kingdom To: | 95 | 1 mg | 50 | |
| Key Organics Limited (BIONET) | 10 days | United Kingdom To: | 95 | 5 mg | 57 | |
| Key Organics Limited (BIONET) | 10 days | United Kingdom To: | 95 | 10 mg | 70 | |
| MedChemExpress | 10 days | United States To: | 99 | 100 mg | 50 | |
| MedChemExpress | 10 days | United States To: | 99 | 500 mg | 150 | |
Description: Names: Diethyl maleate; Maleic acid diethyl ester; Product Description: Diethyl maleate is a maleate ester resulting from the formal condensation of both carboxy groups of maleic acid with ethanol. Diethyl maleate (DEM), a thiol-reactive α,β-unsaturated carbonyl compound, depletes glutathione (GSH) in exposed cells .; Target: Biochemical Assay Reagents; CAS: 141-05-9 | ||||||
| MedChemExpress EU | 10 days | Sweden To: | 99 | 100 mg | 53 | |
| MedChemExpress EU | 10 days | Sweden To: | 99 | 500 mg | 158 | |
Description: Names: Diethyl maleate; Maleic acid diethyl ester; Product Description: Diethyl maleate (DEM) is an orally available, effective glutathione (GSH) depletor that crosses the blood-brain barrier. Diethyl maleate covalently binds irreversibly to GSH via glutathione S-transferase with an in vitro IC50 of 0.1-0.5 mM. Diethyl maleate selectively depletes GSH in liver, lung, and brain tissues, exacerbating oxidative stress and enhancing hyperbaric oxygen toxicity. Diethyl maleate promotes precursor amino acid uptake and in turn promotes GSH synthesis by upregulating the activity of the cystine-glutamate transporter XO-. Diethyl maleate can be used to study redox homeostasis and GSH protection mechanisms in oxidative stress-related diseases such as hyperbaric oxygen injury and metabolic diseases; Target: Biochemical Assay Reagents; CAS: 141-05-9 | ||||||
| Apexbio Technology LLC | 10 days | United States To: | 98 | 100 mg | 75 | |
| Apexbio Technology LLC | 10 days | United States To: | 98 | 500 mg | 229 | |
Description: Name: Diethylmaleate; Maleic acid diethyl ester; CAS: 141-05-9 | ||||||
| Targetmol Chemicals Inc | 30 days | United States To: | 90 | 100 mg | 41 | |
| Targetmol Chemicals Inc | 30 days | United States To: | 90 | 200 mg | 68 | |
| Targetmol Chemicals Inc | 30 days | United States To: | 90 | 500 mg | 124 | |
Description: Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.; CAS: 141-05-9 | ||||||
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