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Home CSSS00020618859

Structure Info

Chemspace ID
CSSS00020618859 (In-Stock Screening Compounds)
MFCD
MFCD00952718
IUPAC Name
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine hydrochloride
Mol formula
C22H25Cl2FN4O3
Mol weight
483 Da
Catalog Number(s)
340967, A199522, A3433, AA01DPWE, AD264106, AG-11097, AG01DPZ6, APB184475556, AR01DQO6, AS-19174, AX19610, B0084-340967, BB4LS-AS-19174, BD630482, BF19610, CD31002884, CSC020618859, D679317, F84968, FG43011, G215465, HY-50895A, LAN-B85429, LN01343504, M12849, S5098, SAB-070107, T1181L, X5007

Properties

LogP
3.75
Heavy atoms count
32
Rotatable bond count
8
Number of rings
4
Carbon bond saturation, Fsp3
0.363
Polar surface area (Å)
69
Hydrogen bond acceptors count
7
Hydrogen bond donors count
1

SDS

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C22H25Cl2FN4O3
Zoom the structure
CSSS00020618859
 

Items Overall 16 items from 5 suppliers

SupplierLead timeShips fromPurityPackPrice, $Qty
Key Organics Limited (BIONET)10 daysUnited Kingdom
To:
981 mg55
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Key Organics Limited (BIONET)10 daysUnited Kingdom
To:
985 mg68
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Key Organics Limited (BIONET)10 daysUnited Kingdom
To:
9810 mg92
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MedChemExpress10 daysUnited States
To:
99100 mg60
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MedChemExpress10 daysUnited States
To:
99500 mg72
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MedChemExpress10 daysUnited States
To:
991 g90
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MedChemExpress10 daysUnited States
To:
995 g180
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MedChemExpress10 daysUnited States
To:
9910mM/1mL66
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Description: Names: Gefitinib (hydrochloride); ZD-1839 hydrochloride; Product Description: Gefitinib hydrochloride (ZD1839 hydrochloride) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC 50 of 33 nM. Gefitinib hydrochloride selectively inhibits EGF-stimulated tumor cell growth (IC 50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib hydrochloride also induces autophagy . Gefitinib hydrochloride has antitumour activity .; Target: EGFR; CAS: 184475-55-6
Apexbio Technology LLC10 daysUnited States
To:
99100 mg61
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Description: Name: Gefitinib hydrochloride; Potent EGFR inhibitor; CAS: 184475-55-6
MedChemExpress EU10 daysSweden
To:
99100 mg63
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MedChemExpress EU10 daysSweden
To:
99500 mg75
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MedChemExpress EU10 daysSweden
To:
991 g95
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MedChemExpress EU10 daysSweden
To:
995 g190
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MedChemExpress EU10 daysSweden
To:
9910mM/1mL69
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Description: Names: Gefitinib (hydrochloride); ZD-1839 hydrochloride; Product Description: Gefitinib hydrochloride (ZD1839 hydrochloride) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib hydrochloride selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib hydrochloride also induces autophagy. Gefitinib hydrochloride has antitumour activity; Target: EGFR; CAS: 184475-55-6
Targetmol Chemicals Inc30 daysUnited States
To:
9950 mg33
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Targetmol Chemicals Inc30 daysUnited States
To:
99100 mg47
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Description: Gefitinib hydrochloride (ZD-1839 hydrochloride) is an orally active selective and potent tyrosine kinase (EGFR) inhibitor. Gefitinib hydrochloride exhibits antitumor activity, selectively inhibits EGF-stimulated tumor cell growth, induces cellular autophagy, improves lung dysfunction, and inhibits inflammation. Gefitinib hydrochloride has antitumor activity, selectively inhibits EGF-stimulated tumor cell growth, induces cellular autophagy, ameliorates lung dysfunction, and inhibits the progression of inflammation and fibrosis.; CAS: 184475-55-6
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