Structure Info
- Chemspace ID
- CSSS00103150359 (In-Stock Screening Compounds)
- MFCD
- MFCD32666983, MFCD31382069
- IUPAC Name
- 4-[(3-chloro-2-fluorophenyl)amino]-7-methoxyquinazolin-6-yl (2R)-2,4-dimethylpiperazine-1-carboxylate hydrochloride
- Mol formula
- C22H24Cl2FN5O3
- Mol weight
- 496 Da
- Catalog Number(s)
- A1004957, AA01V6P5, AG01V6RX, AR01V7GX, BD00966304, BF34533, CSC103150359, HY-18750A, LAN-B71996, M18097, T4249, TS-09013, Y228264, Y3308008, ZXC272321
- Copy structure to query editor
- SMILES
- INCHI
- INCHI key
- MOL
Properties
- LogP
- 4.03
- Heavy atoms count
- 33
- Rotatable bond count
- 5
- Number of rings
- 4
- Carbon bond saturation, Fsp3
- 0.318
- Polar surface area (Å)
- 80
- Hydrogen bond acceptors count
- 6
- Hydrogen bond donors count
- 1
- Zoom the structure
- CSSS00103150359
Items Overall 7 items from 1 supplier
Supplier | Lead time | Ships from | Purity | Pack | Price, $ | Qty |
---|---|---|---|---|---|---|
Targetmol Chemicals Inc | 30 days | United States To: | 99 | 2 mg | 30 | |
Targetmol Chemicals Inc | 30 days | United States To: | 99 | 5 mg | 41 | |
Targetmol Chemicals Inc | 30 days | United States To: | 99 | 10 mg | 59 | |
Targetmol Chemicals Inc | 30 days | United States To: | 99 | 25 mg | 101 | |
Targetmol Chemicals Inc | 30 days | United States To: | 99 | 50 mg | 179 | |
Targetmol Chemicals Inc | 30 days | United States To: | 99 | 100 mg | 295 | |
Targetmol Chemicals Inc | 30 days | United States To: | 99 | 200 mg | 428 | |
Description: AZD3759 (hydrochloride) is an effective, orally active and central nervous system-penetrant EGFR inhibitor. At Km ATP concentrations, the IC50s are 0.2/0.3/0.2 nM for EGFR (L858R)/EGFR (wt)/EGFR (exon 19Del).; CAS: 1626387-81-2 |
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