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Home CSSS00103152045

Structure Info

Chemspace ID
CSSS00103152045 (In-Stock Screening Compounds)
CAS
781613-23-8
MFCD
MFCD28501234, MFCD23726660, MFCD22124889
IUPAC Name
7-{[(3aR,5R,6aS)-2-methyl-octahydrocyclopenta[c]pyrrol-5-yl]methoxy}-N-(3,4-dichloro-2-fluorophenyl)-6-methoxyquinazolin-4-amine
Mol formula
C24H25Cl2FN4O2
Mol weight
491 Da
Catalog Number(s)
27049, 169474, A100327, AA00G3NR, AG00G3QJ, AH51139, AOS00G3QJ, AR00G4FJ, AS-55834, BB4LS-BD335357, BD335357, CD31000807, CSC103152045, F979840, HY-13314, TQ0166, X746318

Properties

LogP
5.25
Heavy atoms count
33
Rotatable bond count
6
Number of rings
5
Carbon bond saturation, Fsp3
0.416
Polar surface area (Å)
60
Hydrogen bond acceptors count
6
Hydrogen bond donors count
1

SDS

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C24H25Cl2FN4O2
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CSSS00103152045
 

Items Overall 14 items from 3 suppliers

SupplierLead timeShips fromPurityPackPrice, $Qty
MedChemExpress10 daysUnited States
To:
991 mg142
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MedChemExpress10 daysUnited States
To:
995 mg300
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MedChemExpress10 daysUnited States
To:
9910 mg580
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MedChemExpress10 daysUnited States
To:
9910mM/1mL324
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Description: Names: Tesevatinib; XL-647; EXEL-7647; KD-019; Product Description: Tesevatinib (XL-647) is an orally available, blood-brain barrier-penetrant inhibitor of the epidermal growth factor receptor ( EGFR ). Tesevatinib significantly reduces cellular viability, with IC 50 values of 11 nM and 102 nM in GBM12 and GBM6, respectively. Tesevatinib also inhibits HER2 ( IC 50 =16.1 nM), VEGFR2 ( IC 50 =1.5 nM), and Src ( IC 50 =10.3 nM). Tesevatinib can inhibit tumor proliferation and exhibits antitumor activity .; Target: EGFR;Src;VEGFR; CAS: 781613-23-8
MedChemExpress EU10 daysSweden
To:
991 mg150
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MedChemExpress EU10 daysSweden
To:
995 mg316
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MedChemExpress EU10 daysSweden
To:
9910 mg611
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MedChemExpress EU10 daysSweden
To:
9910mM/1mL342
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Description: Names: Tesevatinib; XL-647; EXEL-7647; KD-019; Product Description: Tesevatinib (XL-647) is an orally available, blood-brain barrier-penetrant inhibitor of the epidermal growth factor receptor (EGFR). Tesevatinib significantly reduces cellular viability, with IC50 values of 11 nM and 102 nM in GBM12 and GBM6, respectively. Tesevatinib also inhibits HER2 (IC50=16.1 nM), VEGFR2 (IC50=1.5 nM), and Src (IC50=10.3 nM). Tesevatinib can inhibit tumor proliferation and exhibits antitumor activity; Target: EGFR;Src;VEGFR; CAS: 781613-23-8
Targetmol Chemicals Inc30 daysUnited States
To:
981 mg109
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Targetmol Chemicals Inc30 daysUnited States
To:
982 mg158
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Targetmol Chemicals Inc30 daysUnited States
To:
985 mg249
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Targetmol Chemicals Inc30 daysUnited States
To:
9810 mg482
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Targetmol Chemicals Inc30 daysUnited States
To:
9825 mg789
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Targetmol Chemicals Inc30 daysUnited States
To:
9850 mg1,080
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Description: Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor with IC50 values ​​of 0.3, 16, 1.5, 8.7, and 1.4 nM for EGFR, ErbB2, KDR, Flt4, and EphB4.; CAS: 781613-23-8
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