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Home CSSS00160476737

Structure Info


Chemspace ID
CSSS00160476737 (In-Stock Screening Compounds)
MFCD
MFCD21363632, MFCD09038742
IUPAC Name
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)(1,1,2,2,3,3-²H₆)propoxy]quinazolin-4-amine
Mol formula
C22H24ClFN4O3
Mol weight
453 Da
Catalog Number(s)
22364, AA01EPO7, AG01EPQZ, AR01EQFZ, AX65971, CSC160476737, G14127, G304008, HY-50895S1, TMIJ-0147, Y3309922

Properties

LogP
3.75
Heavy atoms count
31
Rotatable bond count
8
Number of rings
4
Carbon bond saturation, Fsp3
0.363
Polar surface area (Å)
69
Hydrogen bond acceptors count
7
Hydrogen bond donors count
1

SDS

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Items Overall 2 items from 2 suppliers

SupplierLead timeShips fromPurityPackPrice, $Qty
MedChemExpress10 daysUnited States
To:
981 mg558
Go to cartEnquire
Description: Names: Gefitinib-d6; ZD1839-d6; Product Description: Gefitinib-d 6 is the deuterium labeled Gefitinib. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity; Target: Autophagy;EGFR; CAS: 1228664-49-0
MedChemExpress EU10 daysSweden
To:
981 mg588
Go to cartEnquire
Description: Names: Gefitinib-d6; ZD1839-d6; Product Description: Gefitinib-d6 is the deuterium labeled Gefitinib. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity; Target: Autophagy;EGFR; CAS: 1228664-49-0
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