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Home CSSS00160996827

Structure Info

Chemspace ID
CSSS00160996827 (In-Stock Screening Compounds)
MFCD
MFCD31744533, MFCD07127712
IUPAC Name
1-[4-({4-[(3,4-dichloro-2-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)piperidin-1-yl]prop-2-en-1-one hydrochloride
Mol formula
C23H22Cl3FN4O3
Mol weight
528 Da
Catalog Number(s)
A1004960, AA01V4KU, AG-B37264, AG01V4NM, AR01V5CM, BD00959947, BF31786, BP168498, CSC160996827, F90203, LAN-B70474, M22736, P215780, Q70188, T8758, TS-09881, Y3305293, ZXC369397

Properties

LogP
4.5
Heavy atoms count
34
Rotatable bond count
6
Number of rings
4
Carbon bond saturation, Fsp3
0.26
Polar surface area (Å)
77
Hydrogen bond acceptors count
6
Hydrogen bond donors count
1

SDS

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C23H22Cl3FN4O3
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CSSS00160996827
 

Items Overall 7 items from 1 supplier

SupplierLead timeShips fromPurityPackPrice, $Qty
Targetmol Chemicals Inc30 daysUnited States
To:
995 mg50
Go to cartEnquire
Targetmol Chemicals Inc30 daysUnited States
To:
9910 mg75
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Targetmol Chemicals Inc30 daysUnited States
To:
9925 mg128
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Targetmol Chemicals Inc30 daysUnited States
To:
9950 mg192
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Targetmol Chemicals Inc30 daysUnited States
To:
99100 mg287
Go to cartEnquire
Targetmol Chemicals Inc30 daysUnited States
To:
99200 mg431
Go to cartEnquire
Targetmol Chemicals Inc30 daysUnited States
To:
99500 mg713
Go to cartEnquire
Description: Poziotinib hydrochloride irreversibly inhibits EGFR (HER1 or ErbB1), including EGFR mutants, HER2, and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. It is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity.; CAS: 1429757-68-5
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