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Home CSSS00161188829

Structure Info

Chemspace ID
CSSS00161188829 (In-Stock Screening Compounds)
MFCD
MFCD32201037, MFCD01750263
IUPAC Name
(4aS,6aR,6bR,8aR,12aR,12bR,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-N-(2,2,2-trifluoroethyl)-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,12b,13,14,14a,14b-icosahydropicene-4a-carboxamide
Mol formula
C33H45F3N2O3
Mol weight
575 Da
Catalog Number(s)
AA01V4GG, AG01V4J8, AR01V588, BF31628, CSC161188829, F96102, HY-112671, LAN-B70659, M23361, MS-30351, T13604, Y1299685, Y226475

Properties

LogP
6.82
Heavy atoms count
41
Rotatable bond count
3
Number of rings
5
Carbon bond saturation, Fsp3
0.818
Polar surface area (Å)
87
Hydrogen bond acceptors count
4
Hydrogen bond donors count
1

SDS

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C33H45F3N2O3
Zoom the structure
CSSS00161188829
 

Items Overall 20 items from 3 suppliers

SupplierLead timeShips fromPurityPackPrice, €Qty
MedChemExpress10 daysUnited States
To:
995 mg186
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MedChemExpress10 daysUnited States
To:
9910 mg319
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MedChemExpress10 daysUnited States
To:
9925 mg637
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MedChemExpress10 daysUnited States
To:
9950 mg951
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MedChemExpress10 daysUnited States
To:
99100 mg1,618
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MedChemExpress10 daysUnited States
To:
9910mM/1mL235
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Description: Names: CDDO-dhTFEA; RTA dh404; Product Description: CDDO-dhTFEA (RTA dh404) is a synthetic oleanane triterpenoid compound which potently activates Nrf2 and inhibits the pro-inflammatory transcription factor NF-κB . CDDO-dhTFEA restores hypertension (MAP), increases Nrf2 and expression of its target genes, attenuates activation of NF-κB and transforming growth factor-β pathways, and reduces glomerulosclerosis, interstitial fibrosis and inflammation in the chronic kidney disease (CKD) rats .; Target: Keap1-Nrf2;NF-κB; CAS: 1191265-33-4
MedChemExpress EU10 daysSweden
To:
995 mg196
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MedChemExpress EU10 daysSweden
To:
9910 mg336
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MedChemExpress EU10 daysSweden
To:
9925 mg671
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MedChemExpress EU10 daysSweden
To:
9950 mg1,002
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MedChemExpress EU10 daysSweden
To:
99100 mg1,704
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MedChemExpress EU10 daysSweden
To:
9910mM/1mL248
Go to cartEnquire
Description: Names: CDDO-dhTFEA; RTA dh404; Product Description: CDDO-dhTFEA (RTA dh404) is a synthetic oleanane triterpenoid compound which potently activates Nrf2 and inhibits the pro-inflammatory transcription factor NF-κB CDDO-dhTFEA restores hypertension (MAP), increases Nrf2 and expression of its target genes, attenuates activation of NF-κB and transforming growth factor-β pathways, and reduces glomerulosclerosis, interstitial fibrosis and inflammation in the chronic kidney disease (CKD) rats; Target: Apoptosis;Keap1-Nrf2;NF-κB; CAS: 1191265-33-4
Targetmol Chemicals Inc30 daysUnited States
To:
991 mg64
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Targetmol Chemicals Inc30 daysUnited States
To:
992 mg93
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Targetmol Chemicals Inc30 daysUnited States
To:
995 mg155
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Targetmol Chemicals Inc30 daysUnited States
To:
9910 mg268
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Targetmol Chemicals Inc30 daysUnited States
To:
9925 mg538
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Targetmol Chemicals Inc30 daysUnited States
To:
9950 mg777
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Targetmol Chemicals Inc30 daysUnited States
To:
99100 mg1,090
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Targetmol Chemicals Inc30 daysUnited States
To:
99500 mg2,170
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Description: CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-κB pro-inflammatory transcription factor. It restores mean arterial pressure (MAP), elevates Nrf2 levels and the expression of related genes, attenuates NF-κB and transforming growth factor-β pathway activation, and mitigates glomerulosclerosis, interstitial fibrosis, and inflammation in rats with chronic kidney disease (CKD).; CAS: 1191265-33-4
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