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Home CSSS00161189048

Structure Info


Chemspace ID
CSSS00161189048 (In-Stock Screening Compounds)
CAS
2230821-27-7
MFCD
MFCD32062811
IUPAC Name
(2S,4R)-1-[(2S)-2-[3-(2-{[5-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)pentyl]oxy}ethoxy)propanamido]-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide
Mol formula
C47H57ClFN7O8S
Mol weight
935 Da
Catalog Number(s)
28597, 198574, A346407, AA01JK4G, ACS-2952, AG01JK78, AR01JKW8, AZ92060, BD00774997, BH92060, BISN0057, BP-28379, CS-0087480, CSC161189048, D80333, F986380, FPD82127, G223000, HY-123921, LAN-B67889, T5437, Y1012751
SMILES
INCHI
INCHI key
MOL

Items Overall 16 items from 3 suppliers

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MedChemExpress10 daysUnited States
To:
995 mg129
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MedChemExpress10 daysUnited States
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9910 mg196
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MedChemExpress10 daysUnited States
To:
9925 mg333
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MedChemExpress10 daysUnited States
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9950 mg500
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MedChemExpress10 daysUnited States
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99100 mg750
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Description: Names: Gefitinib-based PROTAC 3; Product Description: Gefitinib-based PROTAC 3, conjugating an EGFR binding element to a von Hippel-Lindau ligand via a linker, induces EGFR degradation with DC 50 s of 11.7 nM and 22.3 nM in HCC827(exon 19 del) and H3255 (L858R mutantion) cells, respectively .; Target: EGFR;PROTACs; CAS: 2230821-27-7
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MedChemExpress EU10 daysSweden
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995 mg136
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MedChemExpress EU10 daysSweden
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9910 mg207
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MedChemExpress EU10 daysSweden
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9925 mg351
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MedChemExpress EU10 daysSweden
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9950 mg527
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MedChemExpress EU10 daysSweden
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99100 mg790
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Description: Names: Gefitinib-based PROTAC 3; Product Description: Gefitinib-based PROTAC 3, conjugating an EGFR binding element to a von Hippel-Lindau ligand via a linker, induces EGFR degradation with DC50s of 11.7 nM and 22.3 nM in HCC827(exon 19 del) and H3255 (L858R mutantion) cells, respectively; Target: EGFR;PROTACs; CAS: 2230821-27-7
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Targetmol Chemicals Inc30 daysUnited States
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972 mg38
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Targetmol Chemicals Inc30 daysUnited States
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975 mg58
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Targetmol Chemicals Inc30 daysUnited States
To:
9710 mg107
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Targetmol Chemicals Inc30 daysUnited States
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9725 mg178
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Targetmol Chemicals Inc30 daysUnited States
To:
9750 mg272
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Targetmol Chemicals Inc30 daysUnited States
To:
97100 mg393
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Description: Gefitinib-based PROTAC 3, which connects an EGFR binding element to a VHL ligand via a linker, induces EGFR degradation with DC50s of 11.7 nM and 22.3 nM in HCC827 (exon 19 del) and H3255 (L858R mutation) cells, respectively[1].; CAS: 2230821-27-7
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