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Home CSSS06595022199

Structure Info

Chemspace ID
CSSS06595022199 (In-Stock Screening Compounds)
MFCD
MFCD07383023
IUPAC Name
2-{[3-({4-[(3-aminopropyl)amino]butyl}amino)propyl]amino}-N-[(10S,11S,15R,16R)-16-(4-hydroxy-3,5-dimethoxyphenyl)-14-oxo-4,6,13-trioxatetracyclo[7.7.0.0³,⁷.0¹¹,¹⁵]hexadeca-1,3(7),8-trien-10-yl]acetamide
Mol formula
C33H47N5O8
Mol weight
642 Da
Catalog Number(s)
AA024CA5, AG024CCX, BJ61673, HY-106031, T27299

Properties

LogP
-1.46
Heavy atoms count
46
Rotatable bond count
18
Number of rings
5
Carbon bond saturation, Fsp3
0.575
Polar surface area (Å)
175
Hydrogen bond acceptors count
11
Hydrogen bond donors count
6

SDS

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C33H47N5O8
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CSSS06595022199
 

Items Overall 6 items from 2 suppliers

SupplierLead timeShips fromPurityPackPrice, €Qty
MedChemExpress10 daysUnited States
To:
975 mg93
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MedChemExpress10 daysUnited States
To:
9710 mg147
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MedChemExpress10 daysUnited States
To:
9725 mg294
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Description: Names: F-14512; Product Description: F-14512 is a targeted cytotoxic compound that utilizes the polyamine transport system (PTS) to selectively deliver polyamine-containing drugs to cancer cells. F-14512 combines an epipodophyllotoxin core that targets topoisomerase II with a spermine group that acts as a cell delivery vehicle, with improved selectivity for tumor cells. F-14512 exhibits significant cytotoxicity against cells with high PTS activity and demonstrates high potency in multiple human cell lines (median IC 50 =0.18 μM). In the MX1 breast tumor xenograft model, F-14512 exhibits potent antitumor activity .; CAS: 866874-63-7
MedChemExpress EU10 daysSweden
To:
975 mg98
Go to cartEnquire
MedChemExpress EU10 daysSweden
To:
9710 mg155
Go to cartEnquire
MedChemExpress EU10 daysSweden
To:
9725 mg310
Go to cartEnquire
Description: Names: F-14512; Product Description: F-14512 is a targeted cytotoxic compound that utilizes the polyamine transport system (PTS) to selectively deliver polyamine-containing drugs to cancer cells. F-14512 combines an epipodophyllotoxin core that targets topoisomerase II with a spermine group that acts as a cell delivery vehicle, with improved selectivity for tumor cells. F-14512 exhibits significant cytotoxicity against cells with high PTS activity and demonstrates high potency in multiple human cell lines (median IC50=0.18 μM). In the MX1 breast tumor xenograft model, F-14512 exhibits potent antitumor activity; CAS: 866874-63-7
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