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Home CSSS06741697602

Structure Info

Chemspace ID
CSSS06741697602 (In-Stock Screening Compounds)
CAS
2772612-96-9
MFCD
MFCD35065028
IUPAC Name
(3S)-N-(11-{4-[3-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)propyl]piperazin-1-yl}-11-oxoundecyl)-3-{[(2S,4R)-4-hydroxy-1-[(2R)-3-methyl-2-(3-methyl-1,2-oxazol-5-yl)butanoyl]pyrrolidin-2-yl]formamido}-3-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]propanamide
Mol formula
C60H76ClFN10O8S
Mol weight
1152 Da
Catalog Number(s)
AG02DHNI, BN88438, EN300-44825960, HY-147942, T74635

Properties

LogP
7.04
Heavy atoms count
81
Rotatable bond count
28
Number of rings
8
Carbon bond saturation, Fsp3
0.5
Polar surface area (Å)
217
Hydrogen bond acceptors count
13
Hydrogen bond donors count
4

SDS

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C60H76ClFN10O8S
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CSSS06741697602
 

Items Overall 10 items from 2 suppliers

SupplierLead timeShips fromPurityPackPrice, €Qty
MedChemExpress10 daysUnited States
To:
991 mg529
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MedChemExpress10 daysUnited States
To:
995 mg1,324
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MedChemExpress10 daysUnited States
To:
9910 mg2,108
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MedChemExpress10 daysUnited States
To:
9925 mg4,167
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MedChemExpress10 daysUnited States
To:
9950 mg6,667
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Description: Names: MS9449; Product Description: MS9449 is a potent PROTAC EGFR degrader with K d s of 17 nM and 10 nM for EGFR WT and EGFR L858R, respectively. MS9449 effectively induces degradation of mutant EGFRs through both the ubiquitin/proteasome system (UPS) and autophagy/lysosome pathways. MS9449 potently inhibits the proliferation of NSCLC cells. MS9449 can be used for researching anticancer .; Target: EGFR;PROTACs; CAS: 2772612-96-9
MedChemExpress EU10 daysSweden
To:
991 mg558
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MedChemExpress EU10 daysSweden
To:
995 mg1,395
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MedChemExpress EU10 daysSweden
To:
9910 mg2,221
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MedChemExpress EU10 daysSweden
To:
9925 mg4,390
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MedChemExpress EU10 daysSweden
To:
9950 mg7,024
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Description: Names: MS9449; Product Description: MS9449 is a potent PROTAC EGFR degrader with Kds of 17 nM and 10 nM for EGFR WT and EGFR L858R, respectively. MS9449 effectively induces degradation of mutant EGFRs through both the ubiquitin/proteasome system (UPS) and autophagy/lysosome pathways. MS9449 potently inhibits the proliferation of NSCLC cells. MS9449 can be used for researching anticancer; Target: EGFR;PROTACs; CAS: 2772612-96-9
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