Structure Info
- Chemspace ID
- CSSS06744480053 (In-Stock Screening Compounds)
- MFCD
- MFCD09873271
- IUPAC Name
- 7-{[3-({4-[(3-chloro-4-fluorophenyl)amino]-6-methoxyquinazolin-7-yl}oxy)propyl]amino}-N,N-dimethyl-2,1,3-benzoxadiazole-4-sulfonamide
- Mol formula
- C26H25ClFN7O5S
- Mol weight
- 602 Da
- Catalog Number(s)
- AG02DHZU, BN88882, HY-152098, T75015
- Copy structure to query editor
- SMILES
- INCHI
- INCHI key
- MOL
Properties
- LogP
- 3.63
- Heavy atoms count
- 41
- Rotatable bond count
- 10
- Number of rings
- 5
- Carbon bond saturation, Fsp3
- 0.23
- Polar surface area (Å)
- 145
- Hydrogen bond acceptors count
- 10
- Hydrogen bond donors count
- 2
- Zoom the structure
- CSSS06744480053
Items Overall 8 items from 2 suppliers
Supplier | Lead time | Ships from | Purity | Pack | Price, € | Qty |
---|---|---|---|---|---|---|
MedChemExpress | 10 days | United States To: | 99 | 5 mg | 368 | |
MedChemExpress | 10 days | United States To: | 99 | 10 mg | 588 | |
MedChemExpress | 10 days | United States To: | 99 | 25 mg | 1,176 | |
MedChemExpress | 10 days | United States To: | 99 | 50 mg | 1,863 | |
Description: Names: HX103; Product Description: HX103 is an epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI)-based fluorogenic probe. HX103 inhibits EGFR 19 del , EGFR L858R , EGFR wild type and EGFR T790M with IC 50 s of 1.3, 1.5, 4.0 and 977 nM, respectively. HX103 can be used for quantifying active-EGFR to predict agent sensitivity in NSCLC patients with EGFR-activating mutations .; Target: EGFR; CAS: 2566466-98-4 | ||||||
MedChemExpress EU | 10 days | Sweden To: | 99 | 5 mg | 387 | |
MedChemExpress EU | 10 days | Sweden To: | 99 | 10 mg | 620 | |
MedChemExpress EU | 10 days | Sweden To: | 99 | 25 mg | 1,240 | |
MedChemExpress EU | 10 days | Sweden To: | 99 | 50 mg | 1,963 | |
Description: Names: HX103; Product Description: HX103 is an epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI)-based fluorogenic probe. HX103 inhibits EGFR 19 del, EGFR L858R, EGFR wild type and EGFR T790M with IC50s of 1.3, 1.5, 4.0 and 977 nM, respectively. HX103 can be used for quantifying active-EGFR to predict agent sensitivity in NSCLC patients with EGFR-activating mutations; Target: EGFR; CAS: 2566466-98-4 |
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