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Home CSSS07096510970

Structure Info


Chemspace ID
CSSS07096510970 (In-Stock Screening Compounds)
CAS
1110767-45-7
MFCD
MFCD35065393, MFCD15202326
IUPAC Name
(2E)-3-[2,6-dichloro-4-({4-[3-(2,2-dimethyl-1-propoxypropyl)-2-methoxyphenyl]-1,3-thiazol-2-yl}carbamoyl)phenyl]-2-methylprop-2-enoic acid
Mol formula
C29H32Cl2N2O5S
Mol weight
592 Da
Catalog Number(s)
A1949381, AA0294AE, AG0294D6, AR029526, BD01868994, BL84594, BT84594, G66103, HY-148748, T67894, TS-09433, Y228986, Y3117062, Z4869073152, ZXC416367

Properties

LogP
8.49
Heavy atoms count
39
Rotatable bond count
11
Number of rings
3
Carbon bond saturation, Fsp3
0.344
Polar surface area (Å)
98
Hydrogen bond acceptors count
6
Hydrogen bond donors count
2

SDS

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Items Overall 20 items from 4 suppliers

SupplierLead timeShips fromPurityPackPrice, €Qty
MedChemExpress10 daysUnited States
To:
991 mg333
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MedChemExpress10 daysUnited States
To:
995 mg833
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MedChemExpress10 daysUnited States
To:
9910 mg1,324
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MedChemExpress10 daysUnited States
To:
9925 mg2,745
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MedChemExpress10 daysUnited States
To:
9950 mg4,412
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MedChemExpress10 daysUnited States
To:
99100 mg6,765
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MedChemExpress10 daysUnited States
To:
9910mM/1mL1,084
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Description: Names: Butyzamide; Product Description: Butyzamide is an orally active activator of Mpl , a thrombopoietin (TPO) receptor. Butyzamide increases the phosphorylation level of JAK2, STAT3, STAT5 and MAPK. Butyzamide increases the level of human platelets in mouse xenotransplantation assay .; Target: JAK;p38 MAPK;STAT; CAS: 1110767-45-7
MedChemExpress EU10 daysSweden
To:
991 mg351
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MedChemExpress EU10 daysSweden
To:
995 mg878
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MedChemExpress EU10 daysSweden
To:
9910mM/1mL1,142
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Description: Names: Butyzamide; Product Description: Butyzamide is an orally active activator of Mpl, a thrombopoietin (TPO) receptor. Butyzamide increases the phosphorylation level of JAK2, STAT3, STAT5 and MAPK. Butyzamide increases the level of human platelets in mouse xenotransplantation assay; Target: JAK;p38 MAPK;STAT; CAS: 1110767-45-7
Targetmol Chemicals Inc30 daysUnited States
To:
991 mg285
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Targetmol Chemicals Inc30 daysUnited States
To:
995 mg687
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Targetmol Chemicals Inc30 daysUnited States
To:
9910 mg998
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Targetmol Chemicals Inc30 daysUnited States
To:
9925 mg1,480
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Targetmol Chemicals Inc30 daysUnited States
To:
9950 mg1,990
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Targetmol Chemicals Inc30 daysUnited States
To:
99100 mg2,690
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Description: Butyzamide is an effective and oral Mpl activator. It is a novel non-peptide-based molecule with antagonistic effects on thrombopoietin (TPO) receptors, which promotes proliferation of human Mpl (hMpl) expression and mouse pro B cell line Ba/F3. The phosphorylation of JAK2, STAT3, STAT5 and MAPK is induced. Butyzamide has been shown to help increase platelet levels in mouse xenotransplantation trials.; CAS: 1110767-45-7
Enamine LtdTBDUkraine
To:
801 mg99
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Enamine LtdTBDUkraine
To:
802 mg103
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Enamine LtdTBDUkraine
To:
805 mg112
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Enamine LtdTBDUkraine
To:
8010 mg129
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