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Home CSSS14855342050

Structure Info

Chemspace ID
CSSS14855342050 (In-Stock Screening Compounds)
MFCD
MFCD00007881, MFCD35164744
IUPAC Name
(2S,4R)-1-[(2S)-2-(11-{4-[3-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)propyl]piperazin-1-yl}-11-oxoundecanamido)-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide
Mol formula
C55H71ClFN9O7S
Mol weight
1057 Da
Catalog Number(s)
A1467823, AG02E683, BD01384027, BO20283, BP-41596, H41038, HY-157581, T41156

Properties

LogP
6.87
Heavy atoms count
74
Rotatable bond count
25
Number of rings
7
Carbon bond saturation, Fsp3
0.509
Polar surface area (Å)
191
Hydrogen bond acceptors count
12
Hydrogen bond donors count
4

SDS

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C55H71ClFN9O7S
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CSSS14855342050
 

Items Overall 12 items from 2 suppliers

SupplierLead timeShips fromPurityPackPrice, €Qty
MedChemExpress10 daysUnited States
To:
991 mg196
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MedChemExpress10 daysUnited States
To:
995 mg392
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MedChemExpress10 daysUnited States
To:
9910 mg637
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MedChemExpress10 daysUnited States
To:
9925 mg1,275
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MedChemExpress10 daysUnited States
To:
9950 mg2,059
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MedChemExpress10 daysUnited States
To:
99100 mg3,294
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Description: Names: MS39; Product Description: MS39 (compound 6) is a PROTAC targeting EGFR . MS39 is composed of PROTAC target protein ligand N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-(piperazin-1-yl)propoxy)quinazolin-4-amine (HY-W109039) (red part), E3 ligase ligand (S,R,S)-AHPC (HY-125845) (blue part) and PROTAC Linker Undecanedioic acid (HY-W014125) (black part), among which the conjugate of E3 ubiquitin ligase ligand Linker is (S,R,S)-AHPC-CO-C9-acid (HY-139345). MS39 reduces the expression of EGFR and downstream signaling in HCC-827 and H3255 cells. MS39 inhibits the proliferation of H3255 cells .; Target: EGFR;PROTACs; CAS: 2675490-92-1
MedChemExpress EU10 daysSweden
To:
991 mg207
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MedChemExpress EU10 daysSweden
To:
995 mg413
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MedChemExpress EU10 daysSweden
To:
9910 mg671
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MedChemExpress EU10 daysSweden
To:
9925 mg1,343
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MedChemExpress EU10 daysSweden
To:
9950 mg2,169
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MedChemExpress EU10 daysSweden
To:
99100 mg3,471
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Description: Names: MS39; Product Description: MS39 (compound 6) is a PROTAC targeting EGFR. MS39 is composed of PROTAC target protein ligand N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-(piperazin-1-yl)propoxy)quinazolin-4-amine (HY-W109039) (red part), E3 ligase ligand (S,R,S)-AHPC (HY-125845) (blue part) and PROTAC Linker Undecanedioic acid (HY-W014125) (black part), among which the conjugate of E3 ubiquitin ligase ligand Linker is (S,R,S)-AHPC-CO-C9-acid (HY-139345). MS39 reduces the expression of EGFR and downstream signaling in HCC-827 and H3255 cells. MS39 inhibits the proliferation of H3255 cells; Target: EGFR;PROTACs; CAS: 2675490-92-1
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