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Home CSSS14929135600

Structure Info


Chemspace ID
CSSS14929135600 (In-Stock Screening Compounds)
IUPAC Name
(2R)-5,7-bis(methoxymethoxy)-2-(4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one
Mol formula
C20H22O7
Mol weight
374 Da
Catalog Number(s)
HY-139534

Properties

LogP
2.75
Heavy atoms count
27
Rotatable bond count
8
Number of rings
3
Carbon bond saturation, Fsp3
0.35
Polar surface area (Å)
72
Hydrogen bond acceptors count
7
Hydrogen bond donors count
0

SDS

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Items Overall 8 items from 2 suppliers

SupplierLead timeShips fromPurityPackPrice, $Qty
MedChemExpress10 daysUnited States
To:
991 mg480
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MedChemExpress10 daysUnited States
To:
995 mg1,050
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MedChemExpress10 daysUnited States
To:
9910 mg1,700
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MedChemExpress10 daysUnited States
To:
9910mM/1mL865
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Description: Names: ARI-1; Product Description: ARI-1 is an inhibitor of receptor tyrosine kinase-like orphan receptor 1 ( ROR1 ) inhibitor. ARI-1 effectively inhibits aberrant ROR1 expression, which is associated with the development of non-small cell lung cancer (NSCLC) and EGFR-TKI-induced drug resistance. ARI-1 binds to the extracellular Frizzled domain of ROR1 and regulates PI3K / AKT / mTOR signaling in a ROR1-dependent manner. ARI-1 potently inhibits NSCLC cell proliferation and migration and has antitumor activity in vivo .; Target: Apoptosis;ROR
MedChemExpress EU10 daysSweden
To:
991 mg506
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MedChemExpress EU10 daysSweden
To:
995 mg1,107
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MedChemExpress EU10 daysSweden
To:
9910 mg1,791
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MedChemExpress EU10 daysSweden
To:
9910mM/1mL912
Go to cartEnquire
Description: Names: ARI-1; Product Description: ARI-1 is an inhibitor of receptor tyrosine kinase-like orphan receptor 1 (ROR1) inhibitor. ARI-1 effectively inhibits aberrant ROR1 expression, which is associated with the development of non-small cell lung cancer (NSCLC) and EGFR-TKI-induced drug resistance. ARI-1 binds to the extracellular Frizzled domain of ROR1 and regulates PI3K/AKT/mTOR signaling in a ROR1-dependent manner. ARI-1 potently inhibits NSCLC cell proliferation and migration and has antitumor activity in vivo; Target: Apoptosis;ROR
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