Structure Info
- Chemspace ID
- CSSS14929135600 (In-Stock Screening Compounds)
- IUPAC Name
- (2R)-5,7-bis(methoxymethoxy)-2-(4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one
- Mol formula
- C20H22O7
- Mol weight
- 374 Da
- Catalog Number(s)
- HY-139534
- Copy structure to query editor
- SMILES
- INCHI
- INCHI key
- MOL
Properties
- LogP
- 2.75
- Heavy atoms count
- 27
- Rotatable bond count
- 8
- Number of rings
- 3
- Carbon bond saturation, Fsp3
- 0.35
- Polar surface area (Å)
- 72
- Hydrogen bond acceptors count
- 7
- Hydrogen bond donors count
- 0
- Zoom the structure
- CSSS14929135600
Items Overall 8 items from 2 suppliers
Supplier | Lead time | Ships from | Purity | Pack | Price, $ | Qty |
---|---|---|---|---|---|---|
MedChemExpress | 10 days | United States To: | 99 | 1 mg | 480 | |
MedChemExpress | 10 days | United States To: | 99 | 5 mg | 1,050 | |
MedChemExpress | 10 days | United States To: | 99 | 10 mg | 1,700 | |
MedChemExpress | 10 days | United States To: | 99 | 10mM/1mL | 865 | |
Description: Names: ARI-1; Product Description: ARI-1 is an inhibitor of receptor tyrosine kinase-like orphan receptor 1 ( ROR1 ) inhibitor. ARI-1 effectively inhibits aberrant ROR1 expression, which is associated with the development of non-small cell lung cancer (NSCLC) and EGFR-TKI-induced drug resistance. ARI-1 binds to the extracellular Frizzled domain of ROR1 and regulates PI3K / AKT / mTOR signaling in a ROR1-dependent manner. ARI-1 potently inhibits NSCLC cell proliferation and migration and has antitumor activity in vivo .; Target: Apoptosis;ROR | ||||||
MedChemExpress EU | 10 days | Sweden To: | 99 | 1 mg | 506 | |
MedChemExpress EU | 10 days | Sweden To: | 99 | 5 mg | 1,107 | |
MedChemExpress EU | 10 days | Sweden To: | 99 | 10 mg | 1,791 | |
MedChemExpress EU | 10 days | Sweden To: | 99 | 10mM/1mL | 912 | |
Description: Names: ARI-1; Product Description: ARI-1 is an inhibitor of receptor tyrosine kinase-like orphan receptor 1 (ROR1) inhibitor. ARI-1 effectively inhibits aberrant ROR1 expression, which is associated with the development of non-small cell lung cancer (NSCLC) and EGFR-TKI-induced drug resistance. ARI-1 binds to the extracellular Frizzled domain of ROR1 and regulates PI3K/AKT/mTOR signaling in a ROR1-dependent manner. ARI-1 potently inhibits NSCLC cell proliferation and migration and has antitumor activity in vivo; Target: Apoptosis;ROR |
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