Structure Info
- Chemspace ID
- CSSS20456218544 (In-Stock Screening Compounds)
- IUPAC Name
- 1-phenyl-N-(2,3,6-trifluoro-4-{[3-(2-{[(3S,5S)-5-fluoropiperidin-3-yl]amino}pyrimidin-4-yl)pyridin-2-yl]oxy}phenyl)methanesulfonamide
- Mol formula
- C27H24F4N6O3S
- Mol weight
- 589 Da
- Catalog Number(s)
- HY-161672, T87983, Y4181629
- Copy structure to query editor
- SMILES
- INCHI
- INCHI key
- MOL
Properties
- LogP
- 3.37
- Heavy atoms count
- 41
- Rotatable bond count
- 8
- Number of rings
- 5
- Carbon bond saturation, Fsp3
- 0.222
- Polar surface area (Å)
- 118
- Hydrogen bond acceptors count
- 7
- Hydrogen bond donors count
- 3
- Zoom the structure
- CSSS20456218544
Items Overall 10 items from 2 suppliers
| Supplier | Lead time | Ships from | Purity | Pack | Price, $ | Qty |
|---|---|---|---|---|---|---|
| MedChemExpress | 10 days | United States To: | 99 | 5 mg | 460 | |
| MedChemExpress | 10 days | United States To: | 99 | 10 mg | 740 | |
| MedChemExpress | 10 days | United States To: | 99 | 25 mg | 1,550 | |
| MedChemExpress | 10 days | United States To: | 99 | 50 mg | 2,500 | |
| MedChemExpress | 10 days | United States To: | 99 | 100 mg | 4,000 | |
Description: Names: G-5758; Product Description: G-5758 is an orally available IRE1α inhibitor with an IC 50 of 38 nM for XBP1s. G-5758 is well tolerated in multiple myeloma models (KMS-11) at oral doses up to 500 mg/kg in rats. G-5758 exhibits pharmacodynamics comparable to that of induced IRE1 knockdown .; Target: IRE1;Liposome; CAS: 2413455-99-7 | ||||||
| MedChemExpress EU | 10 days | Sweden To: | 99 | 5 mg | 484 | |
| MedChemExpress EU | 10 days | Sweden To: | 99 | 10 mg | 779 | |
| MedChemExpress EU | 10 days | Sweden To: | 99 | 25 mg | 1,633 | |
| MedChemExpress EU | 10 days | Sweden To: | 99 | 50 mg | 2,635 | |
| MedChemExpress EU | 10 days | Sweden To: | 99 | 100 mg | 4,215 | |
Description: Names: G-5758; Product Description: G-5758 is an orally available IRE1α inhibitor with an IC50 of 38 nM for XBP1s. G-5758 is well tolerated in multiple myeloma models (KMS-11) at oral doses up to 500 mg/kg in rats. G-5758 exhibits pharmacodynamics comparable to that of induced IRE1 knockdown; Target: IRE1;Liposome; CAS: 2413455-99-7 | ||||||
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