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Home Compound Library Sets Lead-Like compounds

Lead-Like compounds


Before it was noticed that compounds tend to grow in molar weight and logP while hit-to-lead optimization, there could have been any compounds on the first stages of drug discovery project. Since first high-throughput screening attempts, numerous rules have emerged that restricted the physicochemical parameters of the molecules screened.

A good starting point is a very important part for any research project: lead-likeness physicochemical criteria enhance the chance for the compound to be a hit – thus, raising the quality of the library.
We selected the in-stock lead-like compounds for Chemspace Lead-Like compounds set. Please discover also the Diversity sets of this library that comprise 5, 10 and 15 thousand of compounds.

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methyl (2S,4R)-1-[(5-bromo-2-chlorophenyl)methyl]-4-hydroxypyrrolidine-2-carboxylate
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4-({[1-(2H-1,2,3,4-tetrazol-5-yl)cyclopentyl]amino}methyl)benzoic acid
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