Hit follow-up usually shifts its physChem parameters to less desirable area. Initial library of high quality is a key to enhance the probability of hit obtaining and chance that is would be suitable for follow-up.
Please discover Chemspace Selected Fragments: compounds added to this set have passed the strict Astex physChem filters and are free of PAINS and supposedly toxic reagents.
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![Chemical structure of 2-cyclopropyl-1-methyl-1H-imidazo[4,5-c]pyridine - CSSS00000762761](/st/structure/200/86aec730546b44fa5d13ad289855cd0f/CN1C%2528%253DNC2%253DCN%253DCC%253DC12%2529C1CC1.png)
