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Home Compound Library Sets Spiro Fragments

Spiro Fragments



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Spirocyclic fragment contributes both to rigidity and spherical form of the molecule. Moreover, further modification of the rings that are included into the spirosystem expands the molecule in 3D. This enables high diversity of the analogs.

Discover Chemspace special Spiro Fragments set. All compounds in this set have at least 1 spiro moiety, accord with the Ro3 and are free of PAINS and toxic fragments.

N-[(4-methyl-1H-1,3-benzodiazol-2-yl)methyl]-4-oxaspiro[bicyclo[3.2.0]heptane-6,1'-cyclobutane]-7-amine
CSC027347683
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1-(3-fluoro-2-methylbenzenesulfonyl)-1-azaspiro[3.3]heptane
CSC028265712
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9,9-difluoro-1-oxa-4-azaspiro[5.5]undecane hydrochloride
CSC138538226
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5-[(2-methoxyphenyl)methyl]-8-oxa-5-azaspiro[3.5]nonane
CSC027785011
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