Collection of more than 2100 in-stock compounds, selected on pharmacological similarity base (SEA - Similarity Ensemble Approach) against 50 targets is offered by Chemspace. The threshold for pSEA value was selected greater than 50.* Additional information about BioChemical Classes (enzymes, ion channels, GPCRs, and others) and Diseases involvement (hypertension, cardiovascular, asthma, cancer, neurodegenerative diseases, pain disorders, diabetes-related, and viruses) is added and can be processed.
The library is available as a full or a cherry-picked set. We supply the compounds as solids, DMSO solutions, or dry films in vials or 96, 384 well plates.
It is also possible to prepare compounds sets on the request according to your demands.
* Keiser MJ, Roth BL, Armbruster BN, Ernsberger P, Irwin JJ, Shoichet BK. Relating protein pharmacology by ligand chemistry. Nat Biotech 25 (2), 197-206 (2007)