Last year, a review called “Covalent inhibitors: a rational approach to drug discovery” was published by a group of scientists.
This review aims to provide a short historic overview and focus on recently developed covalent inhibitors (2011–2019), including structural aspects and examples on challenging targets.

We like the fact that the authors talk about both advantages and possible problems of such components in drug discovery like potential off-target toxicity.

Based on this topic, we want to tell you about our Covalent fragments compound libraries which have a huge number of diverse molecules for the start of your research!
You can find out more and download the library here!


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