A new post on Biologics for Research! Today Alice wants to highlight Retinoid-Related Orphan Receptors (RORs) alpha, beta, and gamma, that belong to one nuclear orphan receptor gene subfamily. On the Chemspace Biologics page, we have a great selection of antibodies selective to RORs, related proteins, and ready-to-use biological kits for studying these targets.

And much more! Follow the link to check out all the options!

The ROR gene generates multiple isoforms that exhibit a distinct tissue-specific pattern of expression and regulate different biological processes and target genes. RORs are critical in the regulation of immunity, circadian rhythm, embryonic development, and several metabolic pathways, and have been implicated in several pathologies associated with those processes. To read more about the modulators of RORs check this link!

Recent studies have demonstrated that RORs have emerged as important drug targets for the treatment of various diseases, such as multiple sclerosis, rheumatoid arthritis, and psoriasis.

For more details on that check out this study.