The spectrum of boron-based entities as drug candidates against many diseases has grown tremendously since the first clinically tested boron-based drug, Velcade.

In this review, the authors talk about current boron-containing drug candidates as well as other potent structures containing these atoms. In addition, they also describe the synthesis, key structure-activity relationship, and associated biological activities of such compounds. To read the full article follow the link:


And of course, George prepared a compound set for you!

A set of selected boronic acids and their derivatives is already available for browsing here: