In 2022, SpaceProp was introduced as the first tool for the calculation of property distributions for full fragment spaces. Now, with SpaceProp2, the exploration expands to include new chemical spaces. Research demonstrates that despite being the smallest size, Freedom Space contains molecules with larger TPSA values and more rotatable bonds than all other spaces.
Many thanks to the authors: Justin Lübbers, Uta Lessel, and Matthias Rarey.
