George wanted to remind you about one more of our products today – PROTACs compound sets!

To check out the full information on it visit this page!

Proteolysis-targeting chimeras (PROTACs) are a very promising approach to targeted protein degradation.  

Complementary to traditional PROTACs, several emerging types of PROTACs, such as homobivalent PROTACs based on two E3 ligases (e.g., CRBN, VHL, MDM2, TRIM24), chemical- or biological-based trivalent/multitargeted PROTACs, and covalent PROTACs, are rising for targeted protein degradation. 

The review we presented for you today covers the advantages and disadvantages of the new methodologies. The authors also talk about the possible challenges in the further development of the technology. 

To read the full article follow the link!