Fragment-Based Drug Discovery (FBDD) continues to evolve and make an impact in the pharmaceutical sciences. The article, that George found for you today, features a set of successful Fragment-to-Lead studies, that were published in 2020. The authors do this analysis annually, so they are also giving some information on the upcoming trends in the field. Full text is available here.

Chemspace has also developed a line of compound libraries for FBDD! Today we want to remind you about the General Fragments Library – a collection of small molecules that accord with the Rule of 3, contain no PAINS, and are filtered from toxic/highly reactive compounds by the in-house filters. Check it out by the link: https://chem-space.com/compounds/general-fragments 

We also have a big variety of other Fragments Sets – Covalent, Amine, Fluorine, and a lot more! Explore the whole list here on our website: https://chem-space.com/compounds