We are continuing our series of posts on GPCRs (post #1 here)!


In 2020, an article ‘Impact of GPCR Structures on Drug Discovery’ was published by a group of authors.
Structure-Based Drug Design has been applied to an increasing number of GPCR targets over the past decade and now a few of these drug candidates have entered clinical trials. This is why knowing GPCR structure is highly important.
This thought is the key point of today’s article. The authors talk about ways of structure determination, classification of GPCR targets as well as cover some examples of Structure-Based Drug Design for GPCRs
The ability to determine and explore these structures has been transformative for drug development.


The full text of the article is available here!