Last week, the Nobel Prize in Medicine or Physiology was awarded to Victor Ambros and Gary Ruvkun “for the discovery of microRNA and its role in post-transcriptional gene regulation”.
MicroRNAs (miRNAs) are small non-coding RNAs that play important roles in fundamental cellular processes, including cell proliferation, differentiation, apoptosis, and more. Dysregulation of miRNA expression is associated with a wide range of diseases, such as cancer, cardiovascular, neurodegenerative, inflammatory, autoimmune diseases, and metabolic disorders.
Thus, the importance of Victor Ambros and Gary Ruvkun`s discovery lies not only in understanding of the new mechanism of gene regulation but also in its significant implications for disease research, as well as the potential it opens for therapeutic applications by targeting miRNAs.
At Chemspace, we provide a broad selection of products for miRNA functional and gene regulation studies in vitro and in vivo, enabling the investigation of their involvement in normal biological and disease pathways and the identification and validation of miRNA targets.
You can download the set by following the link.
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