Phenotypic screening (PS) is becoming increasingly popular for identifying bioactive molecules that can modulate disease-related processes, as well as in situations where it is difficult to identify drug targets. A number of new, first-in-class drugs have been discovered through phenotypic screens.

To create a Chemspace Phenotypic Screening Library, we have selected
✔ 29K in-stock molecules
✔ compounds with activity annotations in ChEMBL
✔ compounds with favorable physicochemical profiles

PAINS and toxic molecules have been removed.
Each molecule is annotated with UniProt codes list of reported targets.

For more details please contact us at [email protected].