We are continuing our series of posts on PROTACs. Two previous posts are here (post #1) and here (post #2)!


Last March, a group of researchers published an article on Azo-PROTACs: a novel light-controlled small molecule tool for protein knockdown. 

The molecules themselves are based on an azobenzene moiety, included in the linker.  UV/VIS light induces cis/trans configuration change, which is totally reversible. This approach gives researchers much more control over the effects of a PROTAC inside a cell.

Based on the article, we prepared a great set of azobenzene compounds from our catalog.  
You can use this link to check it out!  
If you have any questions just drop us a line: info@chem-space.com.