The known-for-decades motif of pyrimidin-2-amine has continued to emerge in recent medchem projects. ALIQOPA (copanlisib), approved in September 2017 as an anticancer drug, has two pyrimidin-2-amine motifs in its structure! That’s why we have decided tp update our post on the pyrimidin-2-amines adding 210 new in-stock compounds: https://goo.gl/2G5J5R