George is here with a new article!

Today we are going to talk about quinolones as multipurpose scaffolds in medicinal chemistry. The quinoline hybrids have already been shown excellent results with new targets with a different mode of action as inhibitors of cell proliferation by cell cycle arrest, apoptosis, angiogenesis, disruption of cell migration, and modulation. The review focuses on the mode of action, structure-activity relationship, and molecular docking to reveal the various active pharmacophores of quinoline hybrids. The full text is available by this link.

Of course, we also made a compound set of quinolone derivatives, that might become a great start for your research!

To browse the set follow the link.