A new weekend article from George is here!
Today we are going to focus on a study about anticancer thiophene derivatives discovered over the course of the last decade. Of course, a thiophene-based compound set by Chemspace is ready and waiting till you check it out here.
Thiophene has emerged as one of the relatively well-explored scaffolds for the development of libraries of molecules having a potential anticancer profile. A lot of synthetic effort was involved in creating structurally different derivatives to cover more of the chemical space for more specific target binding.
In this review, the authors have presented the information available on thiophene-based molecules as anticancer agents with a special focus on synthetic methodologies, biological profile, and structure-activity relationship (SAR) studies. You can read the full article here.