Today George found a great article called ‘Urea Derivatives in Modern Drug Discovery and Medicinal Chemistry’ for you!
The urea functionality is inherent to numerous bioactive compounds, including a variety of clinically approved therapies. It is widely used in medicinal chemistry and drug design in order to establish key drug−target interactions and crucial drug-like properties of the compound.

The full text of the article with physicochemical properties, functionality, and drugs with this fragment is available here.

George also brought you a new set of urea derivatives, that might become a great start of your research! The link to the set is provided below: