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Home CSSS00161189048

Structure Info

Chemspace ID
CSSS00161189048 (In-Stock Screening Compounds)
CAS
2230821-27-7
MFCD
MFCD32062811
IUPAC Name
(2S,4R)-1-[(2S)-2-[3-(2-{[5-({4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)pentyl]oxy}ethoxy)propanamido]-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide
Mol formula
C47H57ClFN7O8S
Mol weight
935 Da
Catalog Number(s)
28597, 198574, A346407, AA01JK4G, ACS-2952, AG01JK78, AR01JKW8, AZ92060, BD00774997, BH92060, BISN0057, BP-28379, CS-0087480, CSC161189048, D80333, F986380, FPD82127, G223000, HY-123921, LAN-B67889, T5437, Y1012751

Properties

LogP
5.43
Heavy atoms count
65
Rotatable bond count
23
Number of rings
6
Carbon bond saturation, Fsp3
0.446
Polar surface area (Å)
186
Hydrogen bond acceptors count
12
Hydrogen bond donors count
4

SDS

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C47H57ClFN7O8S
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CSSS00161189048
 

Items Overall 16 items from 3 suppliers

SupplierLead timeShips fromPurityPackPrice, $Qty
MedChemExpress10 daysUnited States
To:
995 mg132
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MedChemExpress10 daysUnited States
To:
9910 mg200
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MedChemExpress10 daysUnited States
To:
9925 mg340
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MedChemExpress10 daysUnited States
To:
9950 mg510
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MedChemExpress10 daysUnited States
To:
99100 mg765
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Description: Names: Gefitinib-based PROTAC 3; Product Description: Gefitinib-based PROTAC 3, conjugating an EGFR binding element to a von Hippel-Lindau ligand via a linker, induces EGFR degradation with DC 50 s of 11.7 nM and 22.3 nM in HCC827(exon 19 del) and H3255 (L858R mutantion) cells, respectively .; Target: EGFR;PROTACs; CAS: 2230821-27-7
MedChemExpress EU10 daysSweden
To:
995 mg139
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MedChemExpress EU10 daysSweden
To:
9910 mg211
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MedChemExpress EU10 daysSweden
To:
9925 mg358
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MedChemExpress EU10 daysSweden
To:
9950 mg538
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MedChemExpress EU10 daysSweden
To:
99100 mg806
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Description: Names: Gefitinib-based PROTAC 3; Product Description: Gefitinib-based PROTAC 3, conjugating an EGFR binding element to a von Hippel-Lindau ligand via a linker, induces EGFR degradation with DC50s of 11.7 nM and 22.3 nM in HCC827(exon 19 del) and H3255 (L858R mutantion) cells, respectively; Target: EGFR;PROTACs; CAS: 2230821-27-7
Targetmol Chemicals Inc30 daysUnited States
To:
972 mg38
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Targetmol Chemicals Inc30 daysUnited States
To:
975 mg58
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Targetmol Chemicals Inc30 daysUnited States
To:
9710 mg107
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Targetmol Chemicals Inc30 daysUnited States
To:
9725 mg178
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Targetmol Chemicals Inc30 daysUnited States
To:
9750 mg272
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Targetmol Chemicals Inc30 daysUnited States
To:
97100 mg393
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Description: Gefitinib-based PROTAC 3, which connects an EGFR binding element to a VHL ligand via a linker, induces EGFR degradation with DC50s of 11.7 nM and 22.3 nM in HCC827 (exon 19 del) and H3255 (L858R mutation) cells, respectively[1].; CAS: 2230821-27-7
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