Structure Info
- Chemspace ID
- CSSS07096510970 (In-Stock Screening Compounds)
- CAS
- 1110767-45-7
- MFCD
- MFCD35065393, MFCD15202326
- IUPAC Name
- (2E)-3-[2,6-dichloro-4-({4-[3-(2,2-dimethyl-1-propoxypropyl)-2-methoxyphenyl]-1,3-thiazol-2-yl}carbamoyl)phenyl]-2-methylprop-2-enoic acid
- Mol formula
- C29H32Cl2N2O5S
- Mol weight
- 592 Da
- Catalog Number(s)
- A1949381, AA0294AE, AG0294D6, AR029526, BD01868994, BL84594, BT84594, G66103, HY-148748, T67894, TS-09433, Y228986, Y3117062, Z4869073152, ZXC416367
- Copy structure to query editor
- SMILES
- INCHI
- INCHI key
- MOL
Properties
- LogP
- 8.49
- Heavy atoms count
- 39
- Rotatable bond count
- 11
- Number of rings
- 3
- Carbon bond saturation, Fsp3
- 0.3448275862069
- Polar surface area (Å)
- 98
- Hydrogen bond acceptors count
- 6
- Hydrogen bond donors count
- 2
- Zoom the structure
- CSSS07096510970
Items Overall 20 items from 4 suppliers
Supplier | Lead time | Ships from | Purity | Pack | Price, $ | Qty |
---|---|---|---|---|---|---|
MedChemExpress | 10 days | United States To: | 99 | 1 mg | 340 | |
MedChemExpress | 10 days | United States To: | 99 | 5 mg | 850 | |
MedChemExpress | 10 days | United States To: | 99 | 10 mg | 1,350 | |
MedChemExpress | 10 days | United States To: | 99 | 25 mg | 2,800 | |
MedChemExpress | 10 days | United States To: | 99 | 50 mg | 4,500 | |
MedChemExpress | 10 days | United States To: | 99 | 100 mg | 6,900 | |
MedChemExpress | 10 days | United States To: | 99 | 10mM/1mL | 1,106 | |
Description: Names: Butyzamide; Product Description: Butyzamide is an orally active activator of Mpl , a thrombopoietin (TPO) receptor. Butyzamide increases the phosphorylation level of JAK2, STAT3, STAT5 and MAPK. Butyzamide increases the level of human platelets in mouse xenotransplantation assay .; Target: JAK;p38 MAPK;STAT; CAS: 1110767-45-7 | ||||||
MedChemExpress EU | 10 days | Sweden To: | 99 | 1 mg | 358 | |
MedChemExpress EU | 10 days | Sweden To: | 99 | 5 mg | 896 | |
MedChemExpress EU | 10 days | Sweden To: | 99 | 10mM/1mL | 1,165 | |
Description: Names: Butyzamide; Product Description: Butyzamide is an orally active activator of Mpl, a thrombopoietin (TPO) receptor. Butyzamide increases the phosphorylation level of JAK2, STAT3, STAT5 and MAPK. Butyzamide increases the level of human platelets in mouse xenotransplantation assay; Target: JAK;p38 MAPK;STAT; CAS: 1110767-45-7 | ||||||
Targetmol Chemicals Inc | 30 days | United States To: | 99 | 1 mg | 285 | |
Targetmol Chemicals Inc | 30 days | United States To: | 99 | 5 mg | 687 | |
Targetmol Chemicals Inc | 30 days | United States To: | 99 | 10 mg | 998 | |
Targetmol Chemicals Inc | 30 days | United States To: | 99 | 25 mg | 1,480 | |
Targetmol Chemicals Inc | 30 days | United States To: | 99 | 50 mg | 1,990 | |
Targetmol Chemicals Inc | 30 days | United States To: | 99 | 100 mg | 2,690 | |
Description: Butyzamide is an effective and oral Mpl activator. It is a novel non-peptide-based molecule with antagonistic effects on thrombopoietin (TPO) receptors, which promotes proliferation of human Mpl (hMpl) expression and mouse pro B cell line Ba/F3. The phosphorylation of JAK2, STAT3, STAT5 and MAPK is induced. Butyzamide has been shown to help increase platelet levels in mouse xenotransplantation trials.; CAS: 1110767-45-7 | ||||||
Enamine Ltd | TBD | Ukraine To: | 80 | 1 mg | 104 | |
Enamine Ltd | TBD | Ukraine To: | 80 | 2 mg | 108 | |
Enamine Ltd | TBD | Ukraine To: | 80 | 5 mg | 118 | |
Enamine Ltd | TBD | Ukraine To: | 80 | 10 mg | 135 |
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