The presence of modification points in the FBDD hits enables their further developability and/or combining of the different hits in one larger molecule. Please also discover our Amine Fragments set that contains compounds with at least one modifiable amino group.
For Chemspace Acid Fragments we selected compounds possessing at least one carboxylic acid group. The compounds are convenient for further modification and fragment follow-up.
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| PhysChem Profile | |||
|---|---|---|---|
| Min | Max | Median | |
| 10 | Heavy Atoms count | 22 | 20 |
| 142 | MW | 300 | 281 |
| -1.2 | SlogP | 3 | 2.1 |
| 1 | HBA count | 3 | 3 |
| 0 | HBD count | 3 | 1 |
| 1 | RB count | 3 | 3 |
| 0 | fsp3 | 0.9 | 0.5 |
| 23 | TPSA | 112 | 67 |
| 1 | Rings count | 7 | 3 |
