The presence of modification points in the FBDD hits enables their further developability and/or combining of the different hits in one larger molecule. Please also discover our Acid Fragments set that contains compounds with at least one modifiable carboxylic group.
Chemspace Amine Fragments is a set of small polar molecules containing at least one primary or secondary amino group. We selected fragment-like compounds that have high fsp3 and moderate TPSA and are convenient for further modification and fragment follow-up.
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| PhysChem Profile | |||
|---|---|---|---|
| Min | Max | Median | |
| 11 | Heavy Atoms count | 22 | 19 |
| 151 | MW | 300 | 268 |
| -1.4 | SlogP | 3 | 1.9 |
| 1 | HBA count | 3 | 3 |
| 1 | HBD count | 3 | 1 |
| 0 | RB count | 3 | 3 |
| 0.1 | fsp3 | 1 | 0.5 |
| 12 | TPSA | 91 | 42 |
| 1 | Rings count | 5 | 2 |
